Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | USP1 | O94782 | 2/20 | 0.32 |
| ▸ | WDR48 | Q8TAF3 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | BACE1 | P56817 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4524203 | 0.82 | TLR7 (0.56) | TLR7 | |
| SCHEMBL4533397 | 0.81 | ADORA2B (0.39) | ADORA2BTLR7MEN1KMT2APDPK1 | |
| SCHEMBL4533404 | 0.79 | TLR7 (0.52) | TLR7MEN1KMT2APDE10ARAB9A | |
| SCHEMBL4539942 | 0.76 | MAPT (0.42) | TLR7MEN1KMT2ARAB9APOLB | |
| SCHEMBL4519659 | 0.74 | ALDH1A1 (0.38) | MEN1KMT2ATDP1RAB9APOLB | |
| SCHEMBL4535692 | 0.72 | SMN1; SMN2 (0.39) | MEN1KMT2ATDP1RAB9AALDH1A1 | |
| SCHEMBL4531255 | 0.72 | MEN1 (0.43) | ADORA2BMEN1KMT2ARAB9APOLB | |
| SCHEMBL1895853 | 0.71 | TLR7 (0.53) | TLR7MEN1KMT2APDE10A | |
| SCHEMBL4532466 | 0.70 | TLR7 (0.43) | TLR7MEN1KMT2APDE10AALDH1A1 | |
| SCHEMBL20796976 | 0.70 | TLR7 (0.46) | TLR7MEN1KMT2ATDP1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8802853-B2 | Arylalkenyl and arylalkynyl substituted imidazoquinolines | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2014-08-12 | — | — | US | disclosed |
| US-20090030030-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY | 2009-01-29 | — | — | US | disclosed |
| EP-1701955-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | 3M Innovative Properties Company (US) | 2006-09-20 | — | — | EP | disclosed |
| WO-2005066170-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2005-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090030030-A1 | ARYLALKENYL AND ARYLALKYNYL SUBSTITUTED IMIDAZOQUINOLINES | IL2, IFNG, IRF3 | ADORA2B 2284/4885TLR7 67/4885MEN1 4795/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.