SCHEMBL4530979

SCHEMBL4530979

C=CC(C=C)CCCCCCCCCCC

nearest known ligand 0.46

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.46
LMNA P02545 1/20 0.42
THRB P10828 1/20 0.42
DNM1 Q05193 2/20 0.42
OPRM1 P35372 1/20 0.40
ADH1B P00325 1/20 0.40
ADH1C P00326 1/20 0.40
ADH1A P07327 1/20 0.40
ADH4 P08319 1/20 0.40
ADH7 P40394 1/20 0.40
GPR84 Q9NQS5 3/20 0.38
FDPS P14324 3/20 0.38
SPHK1 Q9NYA1 1/20 0.38
FFAR1 O14842 1/20 0.38
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4023419 1.00 TSHR (0.46) TSHRLMNATHRBDNM1OPRM1
SCHEMBL28274267 1.00 TSHR (0.46) TSHRLMNATHRBDNM1OPRM1
SCHEMBL4515246 1.00 TSHR (0.46) TSHRLMNATHRBDNM1OPRM1
SCHEMBL6336658 1.00 TSHR (0.46) TSHRLMNATHRBDNM1OPRM1
SCHEMBL6339666 1.00 TSHR (0.46) TSHRLMNATHRBDNM1OPRM1
SCHEMBL27311941 0.97 TSHR (0.42) TSHRLMNATHRBDNM1OPRM1
Water SCHEMBL8815837 0.95 TSHR (0.40) TSHRLMNATHRBDNM1OPRM1
SCHEMBL23195 0.89
SCHEMBL1881575 0.86 ADH1B (0.44) TSHRLMNADNM1ADH1BADH1C
SCHEMBL4939881 0.86 ADH1B (0.44) TSHRLMNADNM1ADH1BADH1C

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109562029-A System for dispensing a cosmetic product 欧莱雅 2019-04-02 CN disclosed
US-20090117160-A1 Compositions for Making up Keratinous Materials L 'OREAL (FR) 2009-05-07 US disclosed
US-20090041696-A1 Compositions for Making Up Keratinous Materials L'OREAL (FR) 2009-02-12 US disclosed
US-20090041695-A1 Compositions for making up keratinous materials L'OREAL (FR) 2009-02-12 US disclosed
US-20080268003-A1 Aqueous solution containing multilaye rinterference pigments L'OREAL (FR) 2008-10-30 US disclosed
US-20080268002-A1 Compositions for Making Up Keratinous Materials L'OREAL (FR) 2008-10-30 US disclosed
US-20080241086-A1 Line of cosmetic compositions L'OREAL (FR) 2008-10-02 US disclosed
US-20080226574-A1 Line of cosmetic compositions L'OREAL (FR) 2008-09-18 US disclosed
US-20080089917-A1 Anhydrous and non-pulverulent, including oily phase; silicones; kits L'OREAL (FR) 2008-04-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080241086-A1 Line of cosmetic compositions CUTA, TYR, RARA TSHR 2682/4885LMNA 562/4885THRB 3665/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.