Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4528078 | 1.00 | P2RX7 (0.47) | P2RX7IL1B | |
| SCHEMBL13706855 | 0.89 | P2RX7 (0.46) | P2RX7IL1B | |
| SCHEMBL11026570 | 0.88 | P2RX7 (0.54) | P2RX7IL1B | |
| SCHEMBL4535427 | 0.88 | P2RX7 (0.54) | P2RX7IL1B | |
| SCHEMBL4535624 | 0.86 | P2RX7 (0.52) | P2RX7IL1B | |
| SCHEMBL4542300 | 0.86 | P2RX7 (0.52) | P2RX7IL1B | |
| SCHEMBL13706853 | 0.84 | HCN1 (0.60) | P2RX7 | |
| SCHEMBL4531028 | 0.84 | P2RX7 (0.60) | P2RX7IL1B | |
| SCHEMBL13706894 | 0.84 | ALDH1A1 (0.58) | P2RX7 | |
| SCHEMBL13706774 | 0.83 | HCN4 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |