Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.76 |
| ▸ | NPC1 | O15118 | 1/20 | 0.76 |
| ▸ | MAPT | P10636 | 1/20 | 0.76 |
| ▸ | RAB9A | P51151 | 1/20 | 0.76 |
| ▸ | LMNA | P02545 | 4/20 | 0.67 |
| ▸ | ESR1 | P03372 | 4/20 | 0.67 |
| ▸ | TSHR | P16473 | 3/20 | 0.67 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.67 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.67 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.65 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | STS | P08842 | 6/20 | 0.64 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.61 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10332518 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL2617118 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL108532 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL10591672 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL21048393 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL828600 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL108412 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL197446 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL10332378 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA | |
| SCHEMBL9355782 | 0.94 | ALDH1A1 (0.83) | ALDH1A1NPC1MAPTRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090176995-A1 | Soluble fullerene derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-07-09 | — | — | US | disclosed |
| US-20090176995-A1 | Soluble fullerene derivatives | NATIONAL UNIVERSITY CORPORATION NAGOYA INSTITUTE OF TECHNOLOGY (JP) | 2009-07-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090176995-A1 | Soluble fullerene derivatives | SOD1, EPCAM, NDUFV2 | ALDH1A1 1019/4885NPC1 1042/4885MAPT 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.