Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB1 | P05556 | 2/20 | 0.50 |
| ▸ | ITGA5 | P08648 | 2/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.50 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.50 |
| ▸ | ITGAV | P06756 | 1/20 | 0.50 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.50 |
| ▸ | ITGB5 | P18084 | 1/20 | 0.50 |
| ▸ | ITGAL | P20701 | 1/20 | 0.50 |
| ▸ | SLC6A12 | P48065 | 5/20 | 0.44 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.44 |
| ▸ | SLC6A13 | Q9NSD5 | 4/20 | 0.44 |
| ▸ | SLC6A1 | P30531 | 3/20 | 0.44 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.44 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.44 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.44 |
| ▸ | GABRR1 | P24046 | 2/20 | 0.44 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2723878 | 1.00 | ITGB1 (0.50) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL14004149 | 0.82 | SYK (0.35) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL10681240 | 0.82 | ITGB3 (0.35) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL14031510 | 0.82 | IRAK4 (0.37) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL6603075 | 0.80 | SLC6A1 (0.50) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL630436 | 0.78 | ITGB1 (0.54) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL523230 | 0.77 | BRD4 (0.50) | HTTSYKPDCD1LG2CD274 | |
| SCHEMBL576497 | 0.76 | PDE4A (0.38) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL6001939 | 0.76 | PDE4A (0.38) | ITGB1ITGA5ITGB3ITGB2ITGAV | |
| SCHEMBL24630408 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115109045-A | Preparation method of bio-based heterocyclic monomer and homopolyester thereof | 大连大学 | 2022-09-27 | — | — | CN | claimed |
| CN-117384367-A | Rapidly water-degradable PBAT copolyester prepared from diester monomer containing three-membered rings and preparation method thereof | 康辉新材料科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117384367-A | Rapidly water-degradable PBAT copolyester prepared from diester monomer containing three-membered rings and preparation method thereof | 康辉新材料科技有限公司 | 2024-01-12 | — | — | CN | disclosed |
| CN-117327264-A | Bio-based monomer containing pyrrolidone ring, polyester and preparation method thereof | 江苏康辉新材料科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| CN-117285702-A | PBAT copolyester with adjustable degradation rate in water and preparation method thereof | 康辉新材料科技有限公司 | 2023-12-26 | — | — | CN | disclosed |
| CN-117164833-A | PBS copolyester capable of being rapidly degraded in water prepared from diester monomer containing three-membered ring and preparation method thereof | 江苏康辉新材料科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164836-A | PET copolyester capable of being rapidly degraded in water prepared from rigid monomer and preparation method | 江苏康辉新材料科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164837-A | Ternary ring-containing monomer preparation method for rapidly-degradable PBT copolyester in water | 江苏康辉新材料科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| CN-117164837-A | Ternary ring-containing monomer preparation method for rapidly-degradable PBT copolyester in water | 江苏康辉新材料科技有限公司 | 2023-12-05 | — | — | CN | disclosed |
| US-20220396565-A1 | NOVEL HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2022-12-15 | — | — | US | disclosed |
| WO-1998048804-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |
| EP-0874843-A1 | NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL) 1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1998-11-04 | — | — | EP | disclosed |
| WO-1998027085-A1 | NOVEL CARBOXY SUBSTITUTED CYCLIC CARBOXAMIDE DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1998-06-25 | — | — | WO | disclosed |
| WO-1997022604-A1 | NOVEL SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL)[1,4]DIAZEPANES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-06-26 | — | — | WO | disclosed |
| EP-0777666-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1997-06-11 | — | — | EP | disclosed |
| WO-1997019074-A1 | SUBSTITUTED 4-(1H-BENZIMIDAZOL-2-YL-AMINO)PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | HOECHST MARION ROUSSEL, INC. (US) | 1997-05-29 | — | — | WO | disclosed |
| WO-1996006094-A1 | NOVEL SUBSTITUTED PIPERIDINES USEFUL FOR THE TREATMENT OF ALLERGIC DISEASES | MERRELL PHARMACEUTICALS INC. (US) | 1996-02-29 | — | — | WO | disclosed |
| EP-0044088-B1 | P-METHOXY-BENZOYL DERIVATIVES | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1984-02-22 | — | — | EP | disclosed |
| EP-0044088-A2 | p-Methoxy-benzoyl derivatives | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1982-01-20 | — | — | EP | disclosed |
| EP-0005143-A1 | 1-Benzoyl-2-pyrrolidinone derivative, processes for its preparation and medicaments containing it | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1979-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220396565-A1 | NOVEL HETEROCYCLIC COMPOUNDS | MRPL21, F12, MRPS34 | ITGB1 4047/4885ITGA5 4402/4885ITGB3 4478/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.