Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
| ▸ | CD274 | Q9NZQ7 | 4/20 | 0.32 |
| ▸ | PDCD1LG2 | Q9BQ51 | 2/20 | 0.32 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | GFER | P55789 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGB2 | P05107 | 1/20 | 0.31 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001939 | 1.00 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DSYK | |
| SCHEMBL14004149 | 0.82 | SYK (0.35) | PDE4APDE4BPDE4CPDE4DSYK | |
| SCHEMBL14139681 | 0.79 | SYK (0.32) | SYKFEN1 | |
| SCHEMBL4532111 | 0.76 | ITGB1 (0.50) | SYKCD274PDCD1LG2MAPTFEN1 | |
| SCHEMBL2723878 | 0.76 | ITGB1 (0.50) | SYKCD274PDCD1LG2MAPTFEN1 | |
| SCHEMBL10681240 | 0.74 | ITGB3 (0.35) | SYKCD274PDCD1LG2PDCD1MAPT | |
| SCHEMBL14031510 | 0.74 | IRAK4 (0.37) | SYKCD274PDCD1LG2PDCD1FEN1 | |
| SCHEMBL523230 | 0.74 | BRD4 (0.50) | PDE4APDE4BPDE4CPDE4DSYK | |
| SCHEMBL22255165 | 0.73 | CD274 (0.39) | PDE4ASYKCD274PDCD1LG2PDCD1 | |
| Methacrylic Acid SCHEMBL28260006 | 0.73 | HCAR2 (0.35) | PDE4APDE4BPDE4CPDE4DKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8212072-B2 | Process for the preparation of pregabalin | Divi's Laboratories, Ltd. (IN) | 2012-07-03 | — | — | US | claimed |
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | DIVI'S LABORATORIES LIMITED (IN) | 2012-02-16 | — | — | US | claimed |
| EP-2418194-A1 | Process for the preparation of pregabalin | Divi's Laboratories Limited (IN) | 2012-02-15 | — | — | EP | claimed |
| US-8212072-B2 | Process for the preparation of pregabalin | Divi's Laboratories, Ltd. (IN) | 2012-07-03 | — | — | US | disclosed |
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | DIVI'S LABORATORIES LIMITED (IN) | 2012-02-16 | — | — | US | disclosed |
| EP-2418194-A1 | Process for the preparation of pregabalin | Divi's Laboratories Limited (IN) | 2012-02-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120041212-A1 | PROCESS FOR THE PREPARATION OF PREGABALIN | GABRA5, GABRA6, GABRE | PDE4A 2018/4885PDE4B 1720/4885PDE4C 1905/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.