Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 15/20 | 0.52 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15111141 | 0.84 | MCHR1 (0.66) | MCHR1 | |
| SCHEMBL4537265 | 0.81 | MCHR1 (0.65) | MCHR1 | |
| SCHEMBL15111361 | 0.77 | MCHR1 (0.61) | MCHR1 | |
| SCHEMBL4534424 | 0.76 | LMNA (0.42) | LMNAKDM4EALDH1A1HSD17B10 | |
| Hydrochloric Acid SCHEMBL4314109 | 0.75 | LMNA (0.41) | LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL4534615 | 0.75 | MCHR1 (0.47) | MCHR1KDM4EALDH1A1HSD17B10 | |
| SCHEMBL4542175 | 0.73 | MCHR1 (0.51) | MCHR1ALDH1A1 | |
| SCHEMBL4327172 | 0.72 | MAPT (0.43) | LMNAKDM4EALDH1A1 | |
| SCHEMBL4322909 | 0.72 | LMNA (0.40) | MCHR1LMNAKDM4EALDH1A1HSD17B10 | |
| SCHEMBL15110986 | 0.71 | MCHR1 (0.66) | MCHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | MSD K.K. (JP) | 2009-10-22 | — | — | US | disclosed |
| EP-1939194-A1 | BICYCLIC AROMATIC SUBSTITUTED PYRIDONE DERIVATIVE | BANYU PHARMACEUTICAL CO., LTD. (JP) | 2008-07-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090264426-A1 | Bicyclic aromatic substituted pyridone derivative | PYCR1, CHRM1, MTR | MCHR1 357/4885LMNA 520/4885KDM4E 1819/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.