SCHEMBL453264

SCHEMBL453264

C=Cc1ccc(N(C)C)cc1Cl

nearest known ligand 0.48

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
SLC2A1 P11166 1/20 0.48
BACE1 P56817 4/20 0.44
ALDH1A1 P00352 5/20 0.43
CCR3 P51677 1/20 0.41
TERT O14746 1/20 0.41
APP P05067 1/20 0.41
TSHR P16473 3/20 0.39
KDM4E B2RXH2 1/20 0.39
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.39
ALOX15 P16050 1/20 0.39
HSD17B10 Q99714 1/20 0.39
EGFR P00533 2/20 0.37
APAF1 O14727 1/20 0.35
PSMB5 P28074 1/20 0.34
IP6K1 Q92551 1/20 0.34
PTGS2 P35354 1/20 0.34
INSR P06213 1/20 0.34
NR1H4 Q96RI1 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1002405 0.80 TDP1 (0.55) SLC2A1BACE1ALDH1A1CCR3TERT
SCHEMBL29848301 0.80 TDP1 (0.55) SLC2A1BACE1ALDH1A1CCR3TERT
SCHEMBL3669876 0.78 APAF1 (0.43) ALDH1A1TERTAPPTSHRKDM4E
SCHEMBL13485314 0.77 BACE1 (0.59) SLC2A1BACE1ALDH1A1APPGAA
SCHEMBL11644961 0.76 APP (0.41) ALDH1A1TERTAPPTSHRALOX15
SCHEMBL28728366 0.76 KDM4E (0.47) SLC2A1BACE1ALDH1A1CCR3TERT
SCHEMBL14741400 0.74 CYP2A6 (0.45) ALDH1A1TERTAPPTSHRKDM4E
SCHEMBL2056277 0.73 ALDH1A1 (0.50) SLC2A1ALDH1A1TERTAPPTSHR
SCHEMBL8047416 0.73 PSMB5 (0.50) BACE1ALDH1A1TERTAPPTSHR
SCHEMBL28640552 0.73 BACE1 (0.47) BACE1ALDH1A1TERTAPPTSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2431413-A1 COMPOSITE NANOGRANULES FROM POLYMER/INORGANIC NANOPARTICLES, PREPARATION METHOD THEREOF AND USE OF THE SAME Wuxi Now Materials Corp. (CN) 2012-03-21 EP claimed
US-20120064140-A1 COMPOSITE NANOGRANULES FROM POLYMER/INORGANIC NANOPARTICLES, PREPARATION METHOD THEREOF AND USE OF THE SAME WUXI NOW MATERIALS CORP. (CN) 2012-03-15 US claimed
US-9139430-B2 Composite nanogranules from polymer/inorganic nanoparticles, preparation method thereof and use of the same WUXI NOW MATERIALS CORP. (CN) 2015-09-22 US disclosed
EP-2431413-A1 COMPOSITE NANOGRANULES FROM POLYMER/INORGANIC NANOPARTICLES, PREPARATION METHOD THEREOF AND USE OF THE SAME Wuxi Now Materials Corp. (CN) 2012-03-21 EP disclosed
US-20120064140-A1 COMPOSITE NANOGRANULES FROM POLYMER/INORGANIC NANOPARTICLES, PREPARATION METHOD THEREOF AND USE OF THE SAME WUXI NOW MATERIALS CORP. (CN) 2012-03-15 US disclosed