SCHEMBL453292

SCHEMBL453292

CO[Si](C)(OC)N(C(=O)N(C)C)c1ccccc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 2/20 0.41
ALDH1A1 P00352 3/20 0.39
TSHR P16473 3/20 0.39
GLA P06280 1/20 0.39
KMT2A Q03164 4/20 0.38
KDM4E B2RXH2 3/20 0.38
HPGD P15428 4/20 0.37
HSD17B10 Q99714 2/20 0.37
L3MBTL1 Q9Y468 2/20 0.36
MAPT P10636 1/20 0.36
ALOX15 P16050 1/20 0.36
MEN1 O00255 2/20 0.35
HTT P42858 1/20 0.35
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
POLB P06746 2/20 0.35
RAB9A P51151 3/20 0.34
NPC1 O15118 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9623703 0.83 NPSR1 (0.45) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL2925123 0.72 KMT2A (0.38) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL7938546 0.72 NPSR1 (0.50) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL22680922 0.70 ALDH1A1 (0.46) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL748812 0.70 NPSR1 (0.73) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL762796 0.70 NPSR1 (0.52) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL27960846 0.70 NPSR1 (0.73) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL11129380 0.69 NPSR1 (0.50) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL11674907 0.68 ALDH1A1 (0.52) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL204288 0.67 NPSR1 (0.43) NPSR1ALDH1A1TSHRGLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 195 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3039068-B1 MOISTURE CURABLE COMPOUND WITH AMINO ACIDS MOMENTIVE PERFORMANCE MAT INC (US) 2020-12-16 EP claimed
EP-3074450-B1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MAT INC (US) 2020-11-11 EP claimed
US-10174169-B2 Moisture curable compound with metal-arene complexes MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2019-01-08 US claimed
US-9976028-B2 Curable coating compositions of silane functional polymers KING INDUSTRIES (US) 2018-05-22 US claimed
US-9944770-B2 Moisture curable compound with thiourea MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-04-17 US claimed
US-9914809-B2 Moisture curable composition with amino acids MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2018-03-13 US claimed
EP-2614107-B1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MAT INC (US) 2018-02-21 EP claimed
US-20170260335-A1 MOISTURE CURABLE COMPOUND WITH METAL-ARENE COMPLEXES MOMENTIVE PERFORMANCE MATERIALS INC. 2017-09-14 US claimed
US-20170174840-A1 MOISTURE CURABLE SILICONE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2017-06-22 US claimed
US-9663621-B2 Moisture curable compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2017-05-30 US claimed
WO-2013158236-A2 MOSITURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-10-24 WO claimed
EP-2614107-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION Momentive Performance Materials Inc. (US) 2013-07-17 EP claimed
WO-2013101755-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013101751-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-07-04 WO claimed
WO-2013090132-A2 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013090127-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITIONS MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-06-20 WO claimed
WO-2013071078-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS, INC. (US) 2013-05-16 WO claimed
WO-2013070227-A1 MOISTURE CURABLE COMPOSITION OF A POLYMER HAVING SILYL GROUPS MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2013-05-16 WO claimed
US-20120065308-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. 2012-03-15 US claimed
WO-2012033886-A1 MOISTURE CURABLE ORGANOPOLYSILOXANE COMPOSITION MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2012-03-15 WO claimed