Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7938546 | 0.90 | NPSR1 (0.50) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL22680922 | 0.86 | ALDH1A1 (0.46) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL453292 | 0.83 | NPSR1 (0.41) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL8387202 | 0.79 | NPSR1 (0.43) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL9796749 | 0.79 | HDAC6 (0.42) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL4433309 | 0.78 | NPSR1 (0.41) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL9468244 | 0.76 | KDM4E (0.49) | NPSR1ALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL9804578 | 0.74 | KMT2A (0.42) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL11742976 | 0.74 | L3MBTL1 (0.40) | NPSR1ALDH1A1GLATSHRKMT2A | |
| SCHEMBL748812 | 0.74 | NPSR1 (0.73) | NPSR1ALDH1A1GLATSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079206-A | For obtaining high molecular weight/narrow distribution addition homo- or copolymers by controlled bulk polymerization; silcon, germanium or tin organic compounds; cocatalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0413464-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| EP-0413465-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| EP-0405785-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-02 | — | — | EP | disclosed |
| US-4008198-A | POLYSILOXANE | WACKER-CHEMIE GMBH (DT) | 1977-02-15 | — | — | US | disclosed |