SCHEMBL204288

SCHEMBL204288

CC(=O)N(c1ccccc1)[Si](C)(C)N(C(C)=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPSR1 Q6W5P4 1/20 0.43
ALDH1A1 P00352 4/20 0.41
TSHR P16473 3/20 0.41
GLA P06280 1/20 0.41
KMT2A Q03164 6/20 0.40
NPC1 O15118 2/20 0.39
RAB9A P51151 1/20 0.39
MTNR1A P48039 1/20 0.39
MTNR1B P49286 1/20 0.39
KDM4E B2RXH2 1/20 0.39
MEN1 O00255 4/20 0.39
CRHBP P24387 1/20 0.39
CRHR2 Q13324 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.38
APAF1 O14727 1/20 0.38
CYP2C19 P33261 2/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
CYP1A2 P05177 1/20 0.37
MAPT P10636 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8387202 0.87 NPSR1 (0.43) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL508790 0.87 NPSR1 (0.43) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL9151256 0.82 MAPT (0.40) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL202695 0.79 KMT2A (0.39) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL9422275 0.76 KMT2A (0.40) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL10508349 0.76 ALDH1A1 (0.41) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL7938546 0.76 NPSR1 (0.50) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL4433309 0.72 NPSR1 (0.41) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL130476 0.72 CRHBP (0.56) NPSR1ALDH1A1TSHRGLAKMT2A
SCHEMBL741752 0.72 NPSR1 (0.64) NPSR1ALDH1A1TSHRGLAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 92 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114752322-A Low-density high-strength flame-retardant adhesive 广东高士高科实业有限公司 2022-07-15 CN claimed
EP-2875074-B1 ORGANOSILOXANE COMPOSITIONS DOW SILICONES CORP (US) 2019-09-18 EP claimed
US-9567503-B2 Organosiloxane compositions DOW CORNING CORPORATION (US) 2017-02-14 US claimed
US-20150175863-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2015-06-25 US claimed
EP-2875074-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2015-05-27 EP claimed
WO-2014013038-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2014-01-23 WO claimed
EP-2493984-A2 PAINTABLE ELASTOMER Dow Corning Corporation (US) 2012-09-05 EP claimed
EP-2493985-A1 ORGANOSILOXANE COMPOSITIONS Dow Corning Corporation (US) 2012-09-05 EP claimed
US-20120214925-A1 Organosiloxane Compositions DOW CORNING CORPORATION (US) 2012-08-23 US claimed
US-20120214902-A1 Paintable Elastomer DOW CORNING EUROPE SA (BE) 2012-08-23 US claimed
WO-2011051173-A1 ORGANOSILOXANE COMPOSITIONS DOW CORNING CORPORATION (US) 2011-05-05 WO claimed
WO-2011051236-A2 PAINTABLE ELASTOMER DOW CORNING CORPORATION (US) 2011-05-05 WO claimed
US-11814553-B2 Adhesive DOW SILICONES CORPORATION (US) 2023-11-14 US disclosed
CN-112823193-B Adhesive agent 美国陶氏有机硅公司 2023-09-15 CN disclosed
CN-114752322-A Low-density high-strength flame-retardant adhesive 广东高士高科实业有限公司 2022-07-15 CN disclosed
US-20210380856-A1 ADHESIVE DOW SILICONES CORPORATION 2021-12-09 US disclosed
EP-0271296-A2 Syntactic sealants DOW CORNING CORPORATION (US) 1988-06-15 EP disclosed
US-4555420-A DIFUNCTIONAL NITROGEN-CONTAINING SILANE CURING AGENTS; LOW MODULUS ENCAPPED POLYSILOXANES GENERAL ELECTRIC COMPANY (US) 1985-11-26 US disclosed
US-4477606-A Water resistant room temperature vulcanizable polyorganosiloxane compositions and method for preparing same TORAY SILICONE CO., LTD. (JP) 1984-10-16 US disclosed
EP-0106363-A2 Water resistant room temperature vulcanizable polyorganosiloxane compositions and method for preparing same Toray Silicone Co., Ltd. (JP) 1984-04-25 EP disclosed