Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 3/20 | 0.47 |
| ▸ | CMA1 | P23946 | 3/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 3/20 | 0.46 |
| ▸ | ITGB7 | P26010 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.46 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13524993 | 0.88 | CTSL (0.54) | RAB9ACTSGCMA1GAACTSL | |
| SCHEMBL8964444 | 0.83 | ALDH1A1 (0.47) | RAB9ANPC1GAAKDM4EALDH1A1 | |
| SCHEMBL8964517 | 0.83 | ALDH1A1 (0.47) | RAB9ANPC1GAAKDM4EALDH1A1 | |
| SCHEMBL453563 | 0.82 | MAPT (0.48) | RAB9AGAAALDH1A1LMNA | |
| SCHEMBL11906993 | 0.81 | CTSL (0.56) | ITGA4ITGB7CTSL | |
| SCHEMBL6938746 | 0.80 | CA2 (0.59) | RAB9ANPC1TP53SMN1; SMN2PKM | |
| SCHEMBL27808559 | 0.80 | CTSL (0.64) | RAB9ACTSGCMA1GAAALDH1A1 | |
| SCHEMBL8588574 | 0.80 | CA2 (0.59) | RAB9ANPC1TP53SMN1; SMN2PKM | |
| SCHEMBL6850655 | 0.80 | CA2 (0.59) | RAB9ANPC1TP53SMN1; SMN2PKM | |
| SCHEMBL27808561 | 0.80 | CTSL (0.64) | RAB9ACTSGCMA1GAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | claimed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | claimed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | claimed |
| EP-2616169-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | Natrix Separations Inc. (CA) | 2013-07-24 | — | — | EP | disclosed |
| WO-2012037101-A2 | CHROMATOGRAPHY MEMBRANES FOR THE PURIFICATION OF CHIRAL COMPOUNDS | NATRIX SEPARATIONS INC. (CA) | 2012-03-22 | — | — | WO | disclosed |
| US-20120064601-A1 | Chromatography Membranes for the Purification of Chiral Compounds | NATRIX SEPARATIONS INC. (CA) | 2012-03-15 | — | — | US | disclosed |