Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 11/20 | 0.47 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.44 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | P2RY14 | Q15391 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | ABL1 | P00519 | 1/20 | 0.38 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4532545 | 0.95 | GPR119 (0.46) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL4529951 | 0.93 | GPR119 (0.46) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL4347832 | 0.92 | GPR119 (0.56) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL4362305 | 0.91 | GPR119 (0.44) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL4358687 | 0.90 | SMN1; SMN2 (0.46) | KDM4ERAB9A | |
| SCHEMBL4356930 | 0.89 | HDAC4 (0.50) | GPR119PTPN2PTPN1PTPN6HDAC4 | |
| SCHEMBL4353589 | 0.89 | PTPN2 (0.48) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL4531644 | 0.89 | GPR119 (0.47) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL4351363 | 0.89 | GPR119 (0.46) | GPR119PTPN2PTPN1PTPN6KDM4E | |
| SCHEMBL4352809 | 0.89 | GPR119 (0.46) | GPR119PTPN2PTPN1PTPN6KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |