Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC4 | P56524 | 3/20 | 0.50 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.46 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.45 |
| ▸ | USP30 | Q70CQ3 | 3/20 | 0.45 |
| ▸ | GPR119 | Q8TDV5 | 7/20 | 0.43 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4353589 | 0.91 | PTPN2 (0.48) | HDAC4PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL4533099 | 0.89 | GPR119 (0.47) | HDAC4PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL4347832 | 0.89 | GPR119 (0.56) | HDAC4PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL4356877 | 0.89 | ALDH1A1 (0.45) | — | |
| SCHEMBL4529951 | 0.88 | GPR119 (0.46) | HDAC4PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL4536702 | 0.88 | GPR119 (0.49) | PTPN2PTPN1PTPN6USP30GPR119 | |
| SCHEMBL4532545 | 0.88 | GPR119 (0.46) | HDAC4PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL4353381 | 0.88 | GPR119 (0.54) | PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL13586062 | 0.87 | PTPN2 (0.44) | HDAC4PTPN2PTPN1PTPN6GPR119 | |
| SCHEMBL4533472 | 0.86 | KMT2A (0.44) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |