Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 9/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4533099 | 0.93 | GPR119 (0.47) | GPR119KDM4EKMT2APTPN2PTPN1 | |
| SCHEMBL4532545 | 0.91 | GPR119 (0.46) | GPR119KDM4EKMT2APTPN2PTPN1 | |
| SCHEMBL4347832 | 0.91 | GPR119 (0.56) | GPR119KDM4EKMT2APTPN2PTPN1 | |
| SCHEMBL4354226 | 0.90 | KDM4E (0.45) | KDM4EALDH1A1KMT2AMEN1HPGD | |
| SCHEMBL4362305 | 0.90 | GPR119 (0.44) | GPR119KDM4EKMT2APTPN2PTPN1 | |
| SCHEMBL4540129 | 0.89 | ALDH1A1 (0.43) | ALDH1A1KMT2AMEN1HPGDCD274 | |
| SCHEMBL4356930 | 0.88 | HDAC4 (0.50) | GPR119KMT2APTPN2PTPN1PTPN6 | |
| SCHEMBL4353589 | 0.88 | PTPN2 (0.48) | GPR119KDM4EKMT2APTPN2PTPN1 | |
| SCHEMBL4531644 | 0.88 | GPR119 (0.47) | GPR119KDM4EKMT2APTPN2PTPN1 | |
| SCHEMBL4351363 | 0.88 | GPR119 (0.46) | GPR119KDM4EKMT2APTPN2PTPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | claimed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |