Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 2/20 | 0.42 |
| ▸ | ELANE | P08246 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.41 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17433316 | 0.88 | KMT2A (0.57) | KMT2ATHRBELANEMAPTALDH1A1 | |
| SCHEMBL4533571 | 0.87 | ELANE (0.51) | KMT2AMEN1ELANEMAPTPOLB | |
| SCHEMBL17433325 | 0.84 | KMT2A (0.54) | KMT2ATHRBELANEMAPTALDH1A1 | |
| SCHEMBL11023299 | 0.80 | ADRB2 (0.53) | KMT2AMEN1MAPTPOLBALDH1A1 | |
| SCHEMBL8417675 | 0.80 | MEN1 (0.67) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL7259849 | 0.79 | ELANE (0.51) | KMT2AELANEMAPTPOLBALDH1A1 | |
| SCHEMBL6931905 | 0.79 | ELANE (0.51) | KMT2AELANEMAPTPOLBALDH1A1 | |
| SCHEMBL16541705 | 0.79 | THRB (0.43) | KMT2AMEN1THRBPOLBLMNA | |
| SCHEMBL7924912 | 0.79 | POLB (0.49) | KMT2AMEN1THRBMAPTPOLB | |
| SCHEMBL12375081 | 0.78 | MAPT (0.52) | KMT2AMEN1THRBELANEMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6040411-A | Low glass temperature organosiloxanes | CONSORTIUM FUR ELEKTROCHEMISCHE INDUSTRIE GMBH (DE) | 2000-03-21 | — | — | US | disclosed |
| EP-0887399-A1 | Silicones having a low glass transition temperature | Consortium für elektrochemische Industrie GmbH (DE) | 1998-12-30 | — | — | EP | disclosed |