SCHEMBL7924946

SCHEMBL7924946

C=CCOc1cccc(OC(=O)C(=C)C)c1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.45
ALDH1A1 P00352 1/20 0.44
KDM4E B2RXH2 1/20 0.43
NPC1 O15118 1/20 0.43
RAB9A P51151 1/20 0.43
ELANE P08246 1/20 0.43
ADRB2 P07550 1/20 0.43
ADRB1 P08588 1/20 0.43
ADRB3 P13945 1/20 0.43
ACHE P22303 1/20 0.43
MTNR1A P48039 1/20 0.40
KAT6A Q92794 1/20 0.40
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
MAPT P10636 1/20 0.39
KMT2A Q03164 1/20 0.39
SMN1; SMN2 Q16637 1/20 0.39
CHRNB2 P17787 1/20 0.39
CHRNB4 P30926 1/20 0.39
CHRNA3 P32297 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3967118 0.86 ACHE (0.56) GAAALDH1A1KDM4ENPC1RAB9A
SCHEMBL6856068 0.84 MTNR1A (0.48) ALDH1A1KDM4EELANEMTNR1ALMNA
SCHEMBL4533571 0.84 ELANE (0.51) GAAALDH1A1NPC1RAB9AELANE
SCHEMBL218655 0.84 ELANE (0.56) ALDH1A1NPC1RAB9AELANEACHE
SCHEMBL10891338 0.83 TP53 (0.50) ALDH1A1KDM4EELANELMNAMEN1
SCHEMBL29168893 0.83 KDM4E (0.48) GAAALDH1A1KDM4ENPC1RAB9A
SCHEMBL11236258 0.82 POLB (0.50) GAAALDH1A1KDM4EELANEMTNR1A
SCHEMBL29168895 0.81 KDM4E (0.50) GAAALDH1A1KDM4ENPC1RAB9A
SCHEMBL7924216 0.81 KDM4E (0.48) GAAALDH1A1KDM4ENPC1RAB9A
SCHEMBL28741221 0.80 MEN1 (0.65) GAAALDH1A1KDM4ENPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6231714-B1 BONDING PAIR OF SUBSTRATES LOCTITE CORPORATION 2001-05-15 US claimed
WO-2000032550-A1 ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS LOCTITE CORPORATION (US) 2000-06-08 WO claimed
US-6231714-B1 BONDING PAIR OF SUBSTRATES LOCTITE CORPORATION 2001-05-15 US disclosed
WO-2000032550-A1 ALLYLIC PHENYL ETHER (METH)ACRYLATE COMPOSITIONS AND NOVEL ALLYLIC PHENYL ETHER (METH)ACRYLATE MONOMERS LOCTITE CORPORATION (US) 2000-06-08 WO disclosed