Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.43 |
| ▸ | CCR4 | P51679 | 5/20 | 0.43 |
| ▸ | HSD17B3 | P37058 | 4/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | STS | P08842 | 1/20 | 0.35 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | KLK7 | P49862 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL179796 | 0.81 | CCR4 (0.64) | EP300CCR4HSD17B3KDM4EALDH1A1 | |
| SCHEMBL29527262 | 0.81 | CCR4 (0.64) | EP300CCR4HSD17B3KDM4EALDH1A1 | |
| SCHEMBL13730668 | 0.80 | HSP90AA1 (0.30) | EP300 | |
| SCHEMBL3363523 | 0.78 | EP300 (0.69) | EP300CCR4KDM4EALDH1A1HTT | |
| SCHEMBL28131701 | 0.77 | KDM4E (0.50) | KDM4EALDH1A1HPGDGAAHSD17B10 | |
| SCHEMBL17066117 | 0.75 | EP300 (0.41) | EP300CCR4HSD17B3KDM4EALDH1A1 | |
| SCHEMBL3660493 | 0.71 | CCR4 (0.64) | EP300CCR4HSD17B3KDM4EALDH1A1 | |
| SCHEMBL16323066 | 0.67 | ALDH1A1 (0.60) | HSD17B3KDM4EALDH1A1HPGDGAA | |
| SCHEMBL5565883 | 0.65 | CCR4 (0.36) | EP300CCR4KDM4EALDH1A1HPGD | |
| SCHEMBL30122941 | 0.63 | CYP1A2 (0.41) | CCR4KDM4EALDH1A1HTTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170023681-A1 | PERSONAL AND SELF INDICATING RADIATION ALERT DOSIMETER | NEW YORK UNIVERSITY | 2017-01-26 | — | — | US | disclosed |
| EP-2702172-A1 | METHOD FOR DETERMINING CLINICALLY RELEVANT HYPOXIA IN CANCER | Overgaard, Jens (DK) | 2014-03-05 | — | — | EP | disclosed |
| WO-2012146259-A1 | METHOD FOR DETERMINING CLINICALLY RELEVANT HYPOXIA IN CANCER | OVERGAARD JENS (DK) | 2012-11-01 | — | — | WO | disclosed |
| US-7476874-B2 | Self indicating radiation alert dosimeter | JP LABORATORIES, INC. (US) | 2009-01-13 | — | — | US | disclosed |
| US-20060145091-A1 | Self indicating radiation alert dosimeter | JP LABORATORIES INC. | 2006-07-06 | — | — | US | disclosed |