SCHEMBL5565883

SCHEMBL5565883

Cc1c(N)cc2oc(=O)c(N3C(=O)C=CC3=O)c(C)c2c1C

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CCR4 P51679 12/20 0.36
ALDH2 P05091 1/20 0.34
HSP90AA1 P07900 1/20 0.32
CCR6 P51684 1/20 0.32
ALDH1A1 P00352 3/20 0.31
KDM4E B2RXH2 2/20 0.31
HPGD P15428 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MEN1 O00255 1/20 0.31
LMNA P02545 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
MAPT P10636 1/20 0.31
KMT2A Q03164 1/20 0.31
TSHR P16473 1/20 0.31
PPARG P37231 1/20 0.31
NCOA2 Q15596 1/20 0.31
NCOA1 Q15788 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
RXFP1 Q9HBX9 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5048528 0.69 GAA (0.35) CCR4HSP90AA1ALDH1A1KDM4EMEN1
SCHEMBL8310517 0.68 CDK9 (0.36) ALDH2KMT2A
SCHEMBL28131701 0.68 KDM4E (0.50) ALDH2ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL19511786 0.67 MGLL (0.48) HSP90AA1CCR6ALDH1A1LMNAMAPT
Hydrochloric Acid SCHEMBL8308661 0.67 CDK9 (0.35) ALDH2
SCHEMBL3660493 0.66 CCR4 (0.64) CCR4ALDH2ALDH1A1KDM4EHPGD
SCHEMBL17066117 0.65 EP300 (0.41) CCR4ALDH1A1KDM4EHPGDGLA
SCHEMBL29527262 0.65 CCR4 (0.64) CCR4ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL179796 0.65 CCR4 (0.64) CCR4ALDH1A1KDM4EHPGDHSD17B10
SCHEMBL4534137 0.65 EP300 (0.43) CCR4ALDH1A1KDM4EHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7282327-B2 Nucleic acid labeling compounds AFFYMETRIX, INC. (US) 2007-10-16 US claimed