Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EP300 | Q09472 | 1/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 11/20 | 0.63 |
| ▸ | KDM4E | B2RXH2 | 9/20 | 0.63 |
| ▸ | HTT | P42858 | 6/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.63 |
| ▸ | GLA | P06280 | 6/20 | 0.60 |
| ▸ | ATM | Q13315 | 6/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.60 |
| ▸ | KLK7 | P49862 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 7/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.55 |
| ▸ | CASP1 | P29466 | 6/20 | 0.55 |
| ▸ | CASP7 | P55210 | 6/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29527262 | 0.86 | CCR4 (0.64) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL179796 | 0.86 | CCR4 (0.64) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL11296750 | 0.82 | ALDH1A1 (0.78) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL29412863 | 0.82 | EP300 (1.00) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL6627 | 0.82 | EP300 (1.00) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL14160791 | 0.81 | CCR4 (0.61) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL14198859 | 0.79 | EP300 (0.79) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL12651890 | 0.79 | ALDH1A1 (0.72) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL29152148 | 0.78 | ALDH1A1 (0.76) | EP300ALDH1A1KDM4EHTTTDP1 | |
| SCHEMBL4534137 | 0.78 | EP300 (0.43) | EP300ALDH1A1KDM4EHTTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PTE. LTD. (SG) | 2010-01-14 | — | — | US | disclosed |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | EXCRX (SINGAPORE) PTE. LTD. (F.K.A. COMBINATORX (SINGAPORE) PTE LTD.) (SG) | 2008-07-03 | — | — | US | disclosed |
| WO-2008033466-A2 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | COMBINATORX (SINGAPORE) PRE. LTD. (SG) | 2008-03-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100009970-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF VIRAL DISEASES | HTR1A, HTR3B, HTR3A | EP300 2518/4885ALDH1A1 2240/4885KDM4E 192/4885 |
| US-20080161324-A1 | Compositions and methods for treatment of viral diseases | HAVCR2, EIF2AK2, RNASE1 | EP300 2324/4885ALDH1A1 785/4885KDM4E 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.