SCHEMBL453440

SCHEMBL453440

CC(=CCCOc1c(Br)cc(Br)cc1Br)C(=O)O

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.46
THRB P10828 7/20 0.43
THRA P10827 6/20 0.43
MEN1 O00255 5/20 0.43
KMT2A Q03164 5/20 0.43
CYP1A2 P05177 3/20 0.43
CYP2D6 P10635 3/20 0.43
CYP3A4 P08684 1/20 0.43
CYP2C19 P33261 1/20 0.43
ALDH1A1 P00352 3/20 0.41
TDP1 Q9NUW8 2/20 0.41
LMNA P02545 1/20 0.41
SMN1; SMN2 Q16637 1/20 0.41
HSD17B10 Q99714 1/20 0.41
NPY1R P25929 1/20 0.40
NPY2R P49146 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10530252 1.00 KDM4E (0.46) KDM4ETHRBTHRAMEN1KMT2A
SCHEMBL7067548 0.88 THRA (0.39) KDM4ETHRBTHRAMEN1KMT2A
SCHEMBL3177110 0.84 MEN1 (0.38) KDM4ETHRBTHRAMEN1KMT2A
SCHEMBL7067190 0.83 THRA (0.46) KDM4ETHRBTHRAMEN1KMT2A
SCHEMBL453711 0.81 HTR1B (0.54) KDM4EMEN1KMT2ACYP1A2CYP2D6
SCHEMBL7065789 0.79 THRA (0.39) KDM4ETHRBTHRAMEN1KMT2A
SCHEMBL7079451 0.77 HSD17B10 (0.38) KDM4ETHRBTHRAMEN1KMT2A
SCHEMBL3187272 0.76 RAB9A (0.48) KDM4EMEN1KMT2AALDH1A1LMNA
SCHEMBL3865671 0.75 L3MBTL1 (0.47) ALDH1A1HSD17B10
SCHEMBL7074084 0.74 HSD17B10 (0.41) KDM4ETHRBTHRAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 75 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050256219-A1 Photocurable resin composition and optical component JSR CORPORATION (JP) 2005-11-17 US claimed
US-20050124713-A1 Brightness enhancing film composition 3M INNOVATIVE PROPERTIES COMPANY 2005-06-09 US claimed
EP-4224245-A1 SPECTACLE LENS Hoya Lens Thailand Ltd. (TH) 2023-08-09 EP disclosed
EP-4224244-A1 EYEGLASS LENS Hoya Lens Thailand Ltd. (TH) 2023-08-09 EP disclosed
US-20230176250-A1 SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2023-06-08 US disclosed
US-20230111587-A1 SPECTACLE LENS HOYA LENS THAILAND LTD. (TH) 2023-04-13 US disclosed
US-20210223690-A1 PHOTOCURABLE COMPOSITION FOR IMPRINT, METHOD FOR PRODUCING FILM USING THE SAME, METHOD FOR PRODUCING OPTICAL COMPONENT USING THE SAME, METHOD FOR PRODUCING CIRCUIT BOARD USING THE SAME, AND METHOD FOR PRODUCING ELECTRONIC COMPONENT USING THE SAME CANON KK (JP) 2021-07-22 US disclosed
US-11003073-B2 Photocurable composition for imprint, method for producing film using the same, method for producing optical component using the same, method for producing circuit board using the same, and method for producing electronic component using the same CANON KABUSHIKI KAISHA (JP) 2021-05-11 US disclosed
EP-2841255-B1 RESIN PRODUCTION METHOD AND RESIN PRODUCTION APPARATUS CANON KK (JP) 2020-05-13 EP disclosed
US-10293543-B2 Method of producing a patterned film CANON KABUSHIKI KAISHA (JP) 2019-05-21 US disclosed
EP-2758987-B1 METHOD OF FORMING A FILM CANON KK (JP) 2019-03-20 EP disclosed
US-20060187366-A1 MICROSTRUCTURED ARTICLE COMPRISING A POLYMERIZED COMPOSITION HAVING LOW GLASS TRANSITION TEMPERATURE 3M INNOVATIVE PROPERTIES COMPANY 2006-08-24 US disclosed
US-20050256219-A1 Photocurable resin composition and optical component JSR CORPORATION (JP) 2005-11-17 US disclosed
US-20050200278-A1 Polymerizable compositions comprising nanoparticles 3M INNOVATIVE PROPERTIES COMPANY 2005-09-15 US disclosed
US-20050124713-A1 Brightness enhancing film composition 3M INNOVATIVE PROPERTIES COMPANY 2005-06-09 US disclosed
US-20030096172-A1 Hologram recording material composition and hologram recording medium DAISO CO., LTD. (JP) 2003-05-22 US disclosed
US-4829101-A SHELL-CORE POLYMERS ROHM GMBH (DE) 1989-05-09 US disclosed
US-4806348-A Method for inducing antibody formation ROHM GMBH (DE) 1989-02-21 US disclosed
US-4710525-A SHELL-CORE ROHM GMBH (DE) 1987-12-01 US disclosed
US-4059545-A Crosslinked styrene polymer foam having suppressed ignition properties THE DOW CHEMICAL COMPANY (US) 1977-11-22 US disclosed