SCHEMBL453469

SCHEMBL453469

CC(c1ccccc1)c1cc(N)ccc1C(=O)O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.47
MAPT P10636 4/20 0.47
KDM4E B2RXH2 4/20 0.47
CYP3A4 P08684 3/20 0.47
GAA P10253 2/20 0.47
ESR2 Q92731 1/20 0.47
PTPN1 P18031 1/20 0.47
KMT2A Q03164 4/20 0.43
TDP1 Q9NUW8 4/20 0.43
MEN1 O00255 3/20 0.43
THRB P10828 2/20 0.43
RECQL P46063 2/20 0.43
KDR P35968 2/20 0.43
CYP2C9 P11712 2/20 0.43
CYP2C19 P33261 2/20 0.43
HSD17B10 Q99714 2/20 0.43
MCL1 Q07820 2/20 0.43
USP2 O75604 1/20 0.43
POLB P06746 1/20 0.43
PKM P14618 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27245284 0.83 ALDH1A1 (0.50) ALDH1A1MAPTKDM4ECYP3A4GAA
SCHEMBL8767651 0.82 TYR (0.60) ALDH1A1MAPTKDM4EGAAESR2
SCHEMBL8108518 0.82 CSNK2A1 (0.44) ALDH1A1MAPTKDM4EGAAKMT2A
SCHEMBL5925579 0.81 KDM4E (0.55) ALDH1A1MAPTKDM4ECYP3A4GAA
SCHEMBL584940 0.81 ALDH1A1 (0.55) ALDH1A1MAPTKDM4EGAAKMT2A
SCHEMBL10719573 0.77 MCL1 (0.46) ALDH1A1KDM4EGAAPTPN1KMT2A
SCHEMBL18641007 0.76 GRM1 (0.42) ALDH1A1MAPTKDM4EKMT2AMEN1
SCHEMBL28549725 0.76 ALDH1A1 (0.42) ALDH1A1MAPTKDM4EGAAKMT2A
SCHEMBL28566236 0.76 ALDH1A1 (0.42) ALDH1A1MAPTKDM4EGAAKMT2A
SCHEMBL14452298 0.76 ALDH1A1 (0.43) ALDH1A1MAPTKDM4ECYP3A4KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 149 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1095128-B1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT PROCTER & GAMBLE (US) 2005-04-20 EP claimed
US-20050009727-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2005-01-13 US claimed
US-20040116320-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2004-06-17 US claimed
US-20030211963-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY 2003-11-13 US claimed
US-6566312-B2 A softener comprising a perfume which imparts a fresh fragrance to laundered fabrics and is long-lasting; reaction product of primary and or secondary amines and a ketone or aldehyde; time release agents PROCTER & GAMBLE COMPANY 2003-05-20 US claimed
US-20030064899-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY 2003-04-03 US claimed
CN-1335883-A Laundry and Cleaning Compositions PROCTER & GAMBLE (US) 2002-02-13 CN claimed
EP-1144566-A2 LAUNDRY AND CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2001-10-17 EP claimed
EP-1095128-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2001-05-02 EP claimed
WO-2000002981-A2 LAUNDRY AND CLEANING COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO claimed
WO-2000002991-A1 AMINE REACTION COMPOUNDS COMPRISING ONE OR MORE ACTIVE INGREDIENT THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO claimed
EP-0971025-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP claimed
EP-0971024-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP claimed
US-20240206461-A1 DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS ENCAPSYS, LLC (US) 2024-06-27 US disclosed
US-12016963-B2 Freshening compositions with alkoxylated phenols THE PROCTER & GAMBLE COMPANY (US) 2024-06-25 US disclosed
EP-4370644-A1 CONSUMER PRODUCTS COMPRISING DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS The Procter & Gamble Company (US) 2024-05-22 EP disclosed
WO-2000002986-A2 PROCESS FOR PRODUCING PARTICLES OF AMINE REACTION PRODUCT THE PROCTER & GAMBLE COMPANY (US) 2000-01-20 WO disclosed
EP-0971021-A1 Process for producing particles of amine reaction product THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP disclosed
EP-0971025-A1 Amine reaction compounds comprising one or more active ingredient THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP disclosed
EP-0971024-A1 Laundry and cleaning compositions THE PROCTER & GAMBLE COMPANY (US) 2000-01-12 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240206461-A1 DELIVERY PARTICLES WITH HIGH CORE:WALL RATIOS CETP, CHMP4B, HDLBP ALDH1A1 193/4885MAPT 576/4885KDM4E 2355/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.