Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM1 | Q13255 | 1/20 | 0.42 |
| ▸ | TYR | P14679 | 1/20 | 0.41 |
| ▸ | LDHA | P00338 | 1/20 | 0.39 |
| ▸ | LDHB | P07195 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28549725 | 0.84 | ALDH1A1 (0.42) | GRM1TYRALDH1A1MEN1LMNA | |
| SCHEMBL28566236 | 0.84 | ALDH1A1 (0.42) | GRM1TYRALDH1A1MEN1LMNA | |
| SCHEMBL27749720 | 0.83 | TYR (0.42) | GRM1TYRLDHALDHBALDH1A1 | |
| SCHEMBL27749718 | 0.83 | TYR (0.42) | GRM1TYRLDHALDHBALDH1A1 | |
| SCHEMBL3268515 | 0.81 | G6PD (0.49) | TYRLDHALDHBALDH1A1MEN1 | |
| SCHEMBL10492587 | 0.78 | TYR (0.43) | TYRALDH1A1LMNAKMT2AKDM4E | |
| SCHEMBL453469 | 0.76 | ALDH1A1 (0.47) | TYRLDHALDHBALDH1A1MEN1 | |
| SCHEMBL21932426 | 0.76 | GRM1 (0.43) | GRM1LDHALDHBALDH1A1MEN1 | |
| SCHEMBL30389737 | 0.76 | ACE2 (0.51) | GRM1ALDH1A1MEN1LMNAPOLB | |
| SCHEMBL10583690 | 0.76 | TYR (0.46) | GRM1TYRLDHAALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3349761-A1 | HEPATITIS B CORE PROTEIN MODULATORS | Assembly Biosciences, Inc. (US) | 2018-07-25 | — | — | EP | disclosed |
| WO-2017048954-A1 | HEPATITIS B CORE PROTEIN MODULATORS | ASSEMBLY BIOSCIENCES, INC. (US) | 2017-03-23 | — | — | WO | disclosed |