SCHEMBL28566236

SCHEMBL28566236

C[C@@H](c1ccccc1)c1ccc(C(=O)O)c(N)c1[C@@H](C)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.42
KMT2A Q03164 4/20 0.42
MAPT P10636 3/20 0.42
MEN1 O00255 2/20 0.42
THRB P10828 2/20 0.42
MAPK1 P28482 2/20 0.42
LMNA P02545 1/20 0.42
POLB P06746 1/20 0.42
RECQL P46063 1/20 0.42
TYR P14679 1/20 0.41
G6PD P11413 1/20 0.39
CASP7 P55210 1/20 0.39
CASP6 P55212 1/20 0.39
KDM4E B2RXH2 2/20 0.38
ALOX5 P09917 1/20 0.36
GRM1 Q13255 1/20 0.36
VKORC1 Q9BQB6 1/20 0.35
ALOX15 P16050 1/20 0.35
ACE2 Q9BYF1 1/20 0.35
USP2 O75604 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28549725 1.00 ALDH1A1 (0.42) ALDH1A1KMT2AMAPTMEN1THRB
SCHEMBL18641007 0.84 GRM1 (0.42) ALDH1A1KMT2AMAPTMEN1THRB
SCHEMBL7198474 0.83 TYR (0.42) ALDH1A1KMT2AMAPTLMNATYR
SCHEMBL10583690 0.83 TYR (0.46) ALDH1A1KMT2AMAPTLMNATYR
SCHEMBL3268515 0.81 G6PD (0.49) ALDH1A1KMT2AMAPTMEN1THRB
SCHEMBL453469 0.76 ALDH1A1 (0.47) ALDH1A1KMT2AMAPTMEN1THRB
SCHEMBL584940 0.76 ALDH1A1 (0.55) ALDH1A1KMT2AMAPTLMNAPOLB
SCHEMBL16672620 0.74 CRHBP (0.38) ALDH1A1KMT2AMEN1LMNAPOLB
SCHEMBL27749718 0.73 TYR (0.42) ALDH1A1KMT2AMAPTTYRGRM1
SCHEMBL27749720 0.73 TYR (0.42) ALDH1A1KMT2AMAPTTYRGRM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112739686-A Novel process for the preparation of (-) -xylometazoline succinate 赛特瑞恩股份有限公司 2021-04-30 CN claimed
CN-113473975-A Process for preparing functionalized cyclooctenes 坦博公司 2021-10-01 CN disclosed
CN-112739686-A Novel process for the preparation of (-) -xylometazoline succinate 赛特瑞恩股份有限公司 2021-04-30 CN disclosed