SCHEMBL45349

SCHEMBL45349

COC(=O)CC(C)(OO)OOC(C)(CC(=O)OC)OO

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.48
HSD17B10 Q99714 3/20 0.39
MGAM O43451 1/20 0.39
GAA P10253 1/20 0.39
SI P14410 1/20 0.39
MGAM2 Q2M2H8 1/20 0.39
TET2 Q6N021 1/20 0.37
RECQL P46063 2/20 0.35
KMT2A Q03164 3/20 0.32
MEN1 O00255 2/20 0.32
CA12 O43570 2/20 0.32
CA14 Q9ULX7 2/20 0.32
CA2 P00918 1/20 0.32
LMNA P02545 3/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
ALDH1A1 P00352 2/20 0.30
MAPT P10636 1/20 0.30
HTT P42858 1/20 0.30
USP2 O75604 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9146934 0.86 TSHR (0.42) TSHRHSD17B10MGAMGAASI
SCHEMBL915738 0.80 TSHR (0.48) TSHRHSD17B10MGAMGAASI
SCHEMBL10482256 0.80 TSHR (0.46) TSHRHSD17B10MGAMGAASI
SCHEMBL9148867 0.79 TSHR (0.37) TSHRHSD17B10MGAMGAASI
SCHEMBL72719 0.78 TSHR (0.50) TSHRMGAMGAASIMGAM2
SCHEMBL10620343 0.77 TSHR (0.50) TSHRALDH1A1
SCHEMBL19469708 0.75 TSHR (0.40) TSHRGAAALDH1A1
SCHEMBL7947521 0.74 TSHR (0.52) TSHR
Tert-Butyl Hydroperoxide SCHEMBL11199804 0.74 TSHR (0.46) TSHRMGAMGAASIMGAM2
SCHEMBL10617990 0.74 TSHR (0.42) TSHRGAALMNAALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 617 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210403701-A1 CURABLE RESIN COMPOSITION, AND FILM, MOLDED ARTICLE, PREPREG, AND FIBER-REINFORCED PLASTIC USING SAID CURABLE RESIN COMPOSITION MITSUBISHI CHEMICAL CORPORATION (JP) 2021-12-30 US claimed
EP-2432092-B1 KIT FOR ELECTRICAL WIRE WATER-SEALING MATERIAL, ELECTRICAL WIRE WATER-SEALING MATERIAL, WATER-SEALING MEMBER, WATER-SEALED ELECTRICAL WIRE, AND WATER-SEALING METHOD JSR CORP (JP) 2016-05-04 EP claimed
CN-102414947-B Kit for electrical wire water-sealing material, electrical wire water-sealing material, water-sealing member, water-sealed electrical wire, and water-sealing method JSR CORP 2015-01-21 CN claimed
US-8895680-B2 Redox curing-type nonaqueous curable composition KURARAY NORITAKE DENTAL INC. (JP) 2014-11-25 US claimed
US-8729321-B2 Fluoroalkyl iodide and its production process ASAHI GLASS COMPANY, LIMITED (JP) 2014-05-20 US claimed
CN-102414947-A Kit for wire water-stopping material, water-stopping member, water-stopping treated wire, and water-stopping treatment method JSR CORP 2012-04-11 CN claimed
EP-2432092-A1 KIT FOR ELECTRICAL WIRE WATER-SEALING MATERIAL, ELECTRICAL WIRE WATER-SEALING MATERIAL, WATER-SEALING MEMBER, WATER-SEALED ELECTRICAL WIRE, AND WATER-SEALING METHOD JSR Corporation (JP) 2012-03-21 EP claimed
US-20120055693-A1 KIT FOR PREPARING WATER-SEALING MATERIAL FOR ELECTRICAL WIRE, WATER-SEALING MATERIAL FOR ELECTRICAL WIRE, WATER-SEALING MEMBER, WATER-SEALED ELECTRICAL WIRE, AND WATER-SEALING METHOD JSR CORPORATION (JP) 2012-03-08 US claimed
US-20100240798-A1 REDOX-CURING TYPE NONAQUEOUS CURABLE COMPOSITION KURARAY MEDICAL INC. (JP) 2010-09-23 US claimed
EP-1437382-B1 One-part organopolysiloxane gel composition SHINETSU CHEMICAL CO (JP) 2007-09-05 EP claimed
US-7067570-B2 One-part organopolysiloxane gel composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2006-06-27 US claimed
EP-1437382-A1 One-part organopolysiloxane gel composition SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-07-14 EP claimed
US-20040116561-A1 a branched organopolysiloxane with vinyl groups bonded to silicon atoms, an organohydrogenpolysiloxane with silanediol groups, a platinum based catalyst, phosphite triester, and a peroxide compound SHIN-ETSU CHEMICAL CO., LTD. (JP) 2004-06-17 US claimed
JP-1090210-A None JP disclosed
CN-118338879-A Curable composition for dental use 可乐丽则武齿科株式会社 2024-07-12 CN disclosed
US-20240228839-A1 TWO-COMPONENT THERMALLY CONDUCTIVE ADHESIVE COMPOSITION AND TWO-COMPONENT THERMALLY CONDUCTIVE GAP-FILLING GLUE 3M INNOVATIVE PROPERTIES COMPANY 2024-07-11 US disclosed
EP-0841354-A1 FOAM MADE FROM MODIFIED POLYPROPYLENE RESIN AND PROCESS FOR THE PRODUCTION THEREOF KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1998-05-13 EP disclosed
US-5629121-A ADDITION-CONDENSATION COPOLYMER, UNSATURATED POLYESTER TOMOEGAWA PAPER CO., LTD. (JP) 1997-05-13 US disclosed
US-5624779-A Toner for electrophotography and process for producing the same TOMOEGAWA PAPER CO, LTD. (JP) 1997-04-29 US disclosed
JP-S6490210-A HARD COATING COMPOSITION AND ITS CURE KAYAKU NOURY CORP 1989-04-06 JP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100240798-A1 REDOX-CURING TYPE NONAQUEOUS CURABLE COMPOSITION LPO, CDH1, GPX4 TSHR 4823/4885HSD17B10 1751/4885MGAM 4002/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.