SCHEMBL4535384

SCHEMBL4535384

O=[N+](O)c1ccc(OP(=O)([O-])O)c(Cl)c1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PDE7A Q13946 1/20 0.38
MAPT P10636 6/20 0.37
ALDH1A1 P00352 4/20 0.37
LMNA P02545 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HSD17B10 Q99714 1/20 0.36
KMT2A Q03164 3/20 0.36
RAB9A P51151 2/20 0.36
MEN1 O00255 2/20 0.36
GAA P10253 1/20 0.36
PKM P14618 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36
NPC1 O15118 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
CYP2D6 P10635 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium Ion SCHEMBL28734908 0.86 PDE7A (0.50) PDE7AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL6041199 0.80 CA1 (0.41) MAPTALDH1A1LMNASMN1; SMN2KMT2A
SCHEMBL1134003 0.76 CA1 (0.56) PDE7AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL4535386 0.76 CA1 (0.56) PDE7AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL28734906 0.75 CA1 (0.54) PDE7AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL16571909 0.74 PDE7A (0.54) PDE7AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL16571907 0.74 PDE7A (0.54) PDE7AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL35321 0.73 CA1 (0.55) ALDH1A1LMNASMN1; SMN2HSD17B10KMT2A
SCHEMBL8565904 0.73 PDE7A (0.49) PDE7AMAPTALDH1A1LMNASMN1; SMN2
SCHEMBL4535383 0.72 HSD17B10 (0.56) PDE7AMAPTALDH1A1LMNASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4560318-A1 TRACP-5B MEASUREMENT METHOD AND KIT THEREFOR Nitto Boseki Co., Ltd. (JP) 2025-05-28 EP disclosed
CN-119630965-A Method for determining TRACP-5b and kit for use in the method 日东纺绩株式会社 2025-03-14 CN disclosed
WO-2025018136-A1 TRACP-5b MEASUREMENT METHOD AND KIT THEREFOR 日東紡績株式会社 2025-01-23 WO disclosed
US-8080375-B2 Methods and kits for detecting an enzyme capable of modifying a nucleic acid ISEAO TECHNOLOGIES LIMITED (GB) 2011-12-20 US disclosed
US-20090098539-A1 Methods and Kits for Detecting an Enzyme Capable of Modifying a Nucleic Acid ISEAO TECHNOLOGIES LIMITED (GB) 2009-04-16 US disclosed
EP-1888770-A2 IMPROVED METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO Technologies Limited (GB) 2008-02-20 EP disclosed
WO-2006123154-A2 IMPROVED METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO TECHNOLOGIES LIMITED (GB) 2006-11-23 WO disclosed
US-20060257879-A1 Methods and kits for detecting an enzyme capable of modifying a nucleic acid ISEAO TECHNOLOGIES LIMITED (GB) 2006-11-16 US disclosed
EP-1649059-A1 METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO Technologies Limited (GB) 2006-04-26 EP disclosed
WO-2005012567-A1 METHODS AND KITS FOR DETECTING AN ENZYME CAPABLE OF MODIFYING A NUCLEIC ACID ISEAO TECHNOLOGIES LIMITED (GB) 2005-02-10 WO disclosed
US-4206280-A PHOSPHO-MONOESTER SUBSTRATE HAVING ORGANIC INDICATOR RADICAL, STRAIGHT-CHAIN ALIPHATIC ALCOHOL ACTIVATOR HOFFMANN-LA ROCHE INC. (US) 1980-06-03 US disclosed