Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | HSPB1 | P04792 | 3/20 | 0.41 |
| ▸ | TTR | P02766 | 3/20 | 0.40 |
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16859704 | 0.83 | MEN1 (0.38) | CA1CA2CES2CES1MEN1 | |
| SCHEMBL4535384 | 0.80 | PDE7A (0.38) | CA1CA2CES2CES1MEN1 | |
| SCHEMBL6041202 | 0.80 | CA1 (0.57) | CA1CA2CES2CES1MEN1 | |
| SCHEMBL6839971 | 0.80 | CES2 (0.57) | CA1CA2CES2CES1MEN1 | |
| SCHEMBL6041195 | 0.80 | CA1 (0.57) | CA1CA2CES2CES1MEN1 | |
| SCHEMBL6839972 | 0.80 | CES2 (0.57) | CA1CA2CES2CES1MEN1 | |
| SCHEMBL6041193 | 0.76 | ALDH1A1 (0.54) | MEN1KMT2AALDH1A1MAPTHSPB1 | |
| SCHEMBL9655472 | 0.74 | ALDH1A1 (0.42) | MEN1KMT2AALDH1A1MAPTHSPB1 | |
| SCHEMBL19834569 | 0.74 | ALDH1A1 (0.49) | CA1CA2CES2CES1MEN1 | |
| Potassium Ion SCHEMBL28734908 | 0.73 | PDE7A (0.50) | CA1CA2CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024036134-A2 | DEFENSIN PROTEINS FOR INFECTION ASSESSMENT | SRI INTERNATIONAL (US) | 2024-02-15 | — | — | WO | disclosed |
| US-20060234306-A1 | Assay method | GENENTECH, INC. (US) | 2006-10-19 | — | — | US | disclosed |
| US-20050233387-A1 | Assay method | GENENTECH, INC. (US) | 2005-10-20 | — | — | US | disclosed |
| US-20030129675-A1 | Assay method | GENENTECH, INC. | 2003-07-10 | — | — | US | disclosed |
| US-20020004247-A1 | Assay method | GENENTECH, INC. | 2002-01-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060234306-A1 | Assay method | ITGB4, ITGA4, ITGAV | CA1 4109/4885CA2 4680/4885CES2 2454/4885 |
| US-20050233387-A1 | Assay method | ITGB4, ITGA4, ITGAV | CA1 4109/4885CA2 4680/4885CES2 2454/4885 |
| US-20030129675-A1 | Assay method | ITGB4, ITGA4, ITGB6 | CA1 3849/4885CA2 4554/4885CES2 2964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.