Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.48 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
| ▸ | FAAH | O00519 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CHRNB4 | P30926 | 2/20 | 0.46 |
| ▸ | CHRNA3 | P32297 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4517266 | 0.91 | FAAH (0.46) | ALDH1A1MAPTFAAHCHRNB4CHRNA3 | |
| SCHEMBL4524496 | 0.86 | CHRNB4 (0.49) | ALDH1A1FAAHCHRNB4CHRNA3SMN1; SMN2 | |
| SCHEMBL4514656 | 0.82 | DPP4 (0.43) | ALDH1A1CHRNB2CHRNA4 | |
| SCHEMBL4371494 | 0.78 | ALOX5AP (0.45) | ALDH1A1MAPTFAAHCHRNB4CHRNA3 | |
| SCHEMBL4371497 | 0.78 | ALOX5AP (0.45) | ALDH1A1MAPTFAAHCHRNB4CHRNA3 | |
| SCHEMBL23327657 | 0.76 | CYP19A1 (0.54) | ALDH1A1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL30882122 | 0.76 | CYP19A1 (0.54) | ALDH1A1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL22069670 | 0.76 | CYP19A1 (0.57) | ALDH1A1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL2564892 | 0.76 | MAPT (0.53) | ALDH1A1MAPTRAB9ASMN1; SMN2LMNA | |
| SCHEMBL4533897 | 0.75 | DPP4 (0.50) | CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | PLE PATRICK | 2009-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090036474-A1 | Quinazoline derivatives for use against cancer | AQP3, AQP1, F12 | ALDH1A1 2449/4885MAPT 3649/4885FAAH 4329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.