SCHEMBL4535859

SCHEMBL4535859

CCC[C@H](Nc1ccccc1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
FPR2 P25090 1/20 0.49
MME P08473 1/20 0.48
MAPT P10636 3/20 0.45
ALDH1A1 P00352 3/20 0.45
HPGD P15428 1/20 0.45
KMT2A Q03164 3/20 0.44
MEN1 O00255 2/20 0.44
MAPK1 P28482 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
NPC1 O15118 1/20 0.44
RAB9A P51151 1/20 0.44
HDAC3 O15379 2/20 0.43
HDAC4 P56524 2/20 0.43
HDAC1 Q13547 2/20 0.43
HDAC2 Q92769 2/20 0.43
HDAC8 Q9BY41 2/20 0.43
GAA P10253 2/20 0.43
HSD17B10 Q99714 2/20 0.43
ALOX5 P09917 1/20 0.43
POLB P06746 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6130487 1.00 FPR2 (0.49) FPR2MMEMAPTALDH1A1HPGD
SCHEMBL859719 0.89 ALDH1A1 (0.52) MMEMAPTALDH1A1HPGDKMT2A
SCHEMBL29432860 0.89 ALDH1A1 (0.52) MMEMAPTALDH1A1HPGDKMT2A
SCHEMBL4668778 0.88 ALDH1A1 (0.48) MMEMAPTALDH1A1KMT2AMEN1
SCHEMBL7572763 0.86 HDAC8 (0.49) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL18738256 0.86 HDAC8 (0.49) MAPTALDH1A1KMT2AMEN1MAPK1
SCHEMBL5955332 0.86 HPGD (0.51) FPR2MMEMAPTALDH1A1HPGD
SCHEMBL27485422 0.86 FPR2 (0.50) FPR2MMEMAPTALDH1A1HPGD
SCHEMBL4526295 0.85 ALDH1A1 (0.50) MMEMAPTALDH1A1HPGDKMT2A
SCHEMBL8635820 0.85 ALDH1A1 (0.50) MMEMAPTALDH1A1HPGDKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP claimed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP claimed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 WO claimed
WO-2024252336-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF PEPTIDREAM INC. (JP) 2024-12-12 WO claimed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 WO claimed
US-20230028880-A1 CD38-BINDING AGENTS AND USES THEREOF KLEO PHARMACEUTICALS, INC. 2023-01-26 US claimed
EP-3993818-A2 CD38-BINDING AGENTS AND USES THEREOF Kleo Pharmaceuticals, Inc. (US) 2022-05-11 EP claimed
CN-114401732-A CD38 binding agents and uses thereof 克莱奥药品有限公司 2022-04-26 CN claimed
EP-4724459-A1 PEPTIDE COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Peptidream Inc (JP) 2026-04-15 EP disclosed
EP-4724457-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF Rayzebio, Inc. (US) 2026-04-15 EP disclosed
WO-2024254339-A9 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2025-10-16 WO disclosed
US-20250263440-A1 CD38-BINDING AGENTS AND USES THEREOF PEPTIDREAM INC. (JP) 2025-08-21 US disclosed
CN-114269770-B CD38 binding agents and uses thereof 肽梦想株式会社 2025-02-25 CN disclosed
WO-2024254339-A2 RADIOPHARMACEUTICAL COMPOSITIONS TARGETING GLYPICAN-3 AND USES THEREOF RAYZEBIO, INC. (US) 2024-12-12 WO disclosed
EP-1922306-A2 AMIDE DERIVATIVES AS ROCK INHIBITORS Astellas Pharma Inc. (JP) 2008-05-21 EP disclosed
WO-2007026920-A2 AMIDE DERIVATIVES AS ROCK INHIBITORS ASTELLAS PHARMA INC. (JP) 2007-03-08 WO disclosed
CN-1151166-A 3-Amino-2-oxo-1-piperidineacetic acid derivatives as enzyme inhibitors CORVAS INT INC (US) 1997-06-04 CN disclosed
EP-0494716-B1 Enzyme-catalysed preparation of optically active carboxylic acids DSM NV (NL) 1996-08-28 EP disclosed
US-5248608-A Enzyme catalyzed stereospecific hdyrolysis DSM N.V. (NL) 1993-09-28 US disclosed
EP-0494716-A2 Enzyme-catalysed preparation of optically active carboxylic acids DSM N.V. (NL) 1992-07-15 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250263440-A1 CD38-BINDING AGENTS AND USES THEREOF CD38, IGSF11, MCL1 FPR2 3479/4885MME 311/4885MAPT 3840/4885
US-20230028880-A1 CD38-BINDING AGENTS AND USES THEREOF CD38, CD47, CD2 FPR2 1858/4885MME 548/4885MAPT 3934/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.