Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MME | P08473 | 3/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2878630 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4526295 | 1.00 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL28213489 | 0.86 | NAPRT (0.45) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL10767589 | 0.85 | MEN1 (0.45) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL1531518 | 0.85 | MEN1 (0.44) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL6130487 | 0.85 | FPR2 (0.49) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL11196579 | 0.85 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL4535859 | 0.85 | FPR2 (0.49) | ALDH1A1MEN1KMT2APOLBMAPT | |
| SCHEMBL1457767 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1POLBGAALMNAL3MBTL1 | |
| SCHEMBL5928374 | 0.83 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMAPTGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0542525-B1 | Antithrombotic agents | LILLY CO ELI (US) | 1998-07-08 | — | — | EP | disclosed |
| EP-0494716-B1 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM NV (NL) | 1996-08-28 | — | — | EP | disclosed |
| US-5252566-A | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-10-12 | — | — | US | disclosed |
| US-5248608-A | Enzyme catalyzed stereospecific hdyrolysis | DSM N.V. (NL) | 1993-09-28 | — | — | US | disclosed |
| EP-0542525-A2 | Antithrombotic agents | ELI LILLY AND COMPANY (US) | 1993-05-19 | — | — | EP | disclosed |
| EP-0494716-A2 | Enzyme-catalysed preparation of optically active carboxylic acids | DSM N.V. (NL) | 1992-07-15 | — | — | EP | disclosed |