Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 8/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.53 |
| ▸ | METAP1 | P53582 | 2/20 | 0.53 |
| ▸ | TP53 | P04637 | 4/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | CCR1 | P32246 | 2/20 | 0.48 |
| ▸ | CCR5 | P51681 | 2/20 | 0.48 |
| ▸ | CCR8 | P51685 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.48 |
| ▸ | P4HTM | Q9NXG6 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.47 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29784044 | 1.00 | KDM4E (0.57) | KDM4ETDP1CYP1A2METAP1TP53 | |
| SCHEMBL11329633 | 0.82 | CYP1A2 (0.58) | KDM4ETDP1CYP1A2METAP1LMNA | |
| SCHEMBL28802825 | 0.81 | CYP1A2 (0.54) | KDM4ECYP1A2METAP1L3MBTL1POLB | |
| SCHEMBL1672650 | 0.81 | CYP1A2 (0.60) | KDM4ECYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL30527184 | 0.81 | CYP1A2 (0.60) | KDM4ECYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL30198446 | 0.81 | CYP1A2 (0.60) | KDM4ECYP1A2LMNAALDH1A1MAPT | |
| SCHEMBL26674905 | 0.80 | L3MBTL1 (0.51) | KDM4ETDP1CYP1A2METAP1TP53 | |
| SCHEMBL8515946 | 0.80 | KDM4E (0.43) | KDM4ETDP1CYP1A2METAP1TP53 | |
| SCHEMBL8515328 | 0.80 | GRM5 (0.59) | KDM4ETDP1CYP1A2METAP1TP53 | |
| SCHEMBL28091206 | 0.78 | CYP1A2 (0.50) | KDM4ETDP1CYP1A2TP53ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111704604-B | Preparation method of pyridine quinazoline | 湖南速博生物技术有限公司 | 2020-11-17 | — | — | CN | claimed |
| CN-111704604-A | Preparation method of pyridine quinazoline | 湖南速博生物技术有限公司 | 2020-09-25 | — | — | CN | claimed |
| EP-1966184-B1 | PYRIDINYL-QUINAZOLINE DERIVATIVES AND THEIR MEDICAL USE | NEUROSEARCH AS (DK) | 2010-08-25 | — | — | EP | claimed |
| US-20090306102-A1 | 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES | NEUROSEARCH A/S (DK) | 2009-12-10 | — | — | US | claimed |
| EP-1966184-A2 | PYRIDINYL-QUINAZOLINE DERIVATIVES AND THEIR MEDICAL USE | NeuroSearch A/S (DK) | 2008-09-10 | — | — | EP | claimed |
| WO-2007071632-A2 | 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES | NEUROSEARCH A/S (DK) | 2007-06-28 | — | — | WO | claimed |
| US-4764454-A | Color photographic material with color forming ligand compounds and a method of processing | FUJI PHOTO FILM CO., LTD. (JP) | 1988-08-16 | — | — | US | claimed |
| CN-116987076-A | 1,2, 4-triazolo [4,3-a ] pyridine sulfone derivative, and preparation method and application thereof | 贵州大学 | 2023-11-03 | — | — | CN | disclosed |
| CN-113519536-A | Binary compound insecticidal composition | 合肥巨卓农业科技合伙企业(有限合伙) | 2021-10-22 | — | — | CN | disclosed |
| CN-113508817-A | Insecticidal composition of pyridine quinazoline and diazinon | 黑龙江巨卓作物科学有限公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-113475510-A | Binary compound insecticidal composition containing pyridine quinazoline | 黑龙江巨卓作物科学有限公司 | 2021-10-08 | — | — | CN | disclosed |
| CN-111887255-A | Pesticide composition containing spiromesifen and pyridine quinazoline and application thereof | 山东康乔生物科技有限公司 | 2020-11-06 | — | — | CN | disclosed |
| CN-111184034-A | Pesticide composition containing pyridine quinazoline and eucalyptol | 江西中迅农化有限公司 | 2020-05-22 | — | — | CN | disclosed |
| EP-0186870-A2 | Photographic elements and processes utilizing imagewise reduction of ferric ions | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-09 | — | — | EP | disclosed |
| EP-0186869-A2 | Colorless ligand-releasing monomers and polymers and their use to provide dyes with metal ions | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-09 | — | — | EP | disclosed |
| EP-0186868-A2 | Photographic element and process for providing metal complex color images | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1986-07-09 | — | — | EP | disclosed |
| US-4568633-A | THEN REACTING WITH COMPLEXING COMPOUND TO FORM DYE | EASTMAN KODAK COMPANY (US) | 1986-02-04 | — | — | US | disclosed |
| US-4557998-A | AVOIDS COUPLER SOLVENTS | EASTMAN KODAK COMPANY (US) | 1985-12-10 | — | — | US | disclosed |
| US-4555478-A | Photographic element and process for providing metal complex color images | EASTMAN KODAK COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
| US-4555477-A | Photographic element and process utilizing metal complex color masking dyes | EASTMAN KODAK COMPANY (US) | 1985-11-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090306102-A1 | 2-PYRIDIN-2-YL-QUINAZOLINE DERIVATIVES AS POTASSIUM CHANNEL MODULATING AGENTS FOR THE TREATMENT OF RESPIRATORY DISEASES | KCNJ2, KCNQ1, KCNK2 | KDM4E 1023/4885TDP1 3156/4885CYP1A2 1530/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.