Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 6/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.40 |
| ▸ | CCR1 | P32246 | 2/20 | 0.40 |
| ▸ | CCR5 | P51681 | 2/20 | 0.40 |
| ▸ | CCR8 | P51685 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | ALPL | P05186 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.40 |
| ▸ | ALPI | P09923 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3786821 | 0.84 | HTT (0.47) | KDM4ECYP1A2L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8778873 | 0.81 | CYP1A2 (0.44) | KDM4ECYP1A2L3MBTL1SMN1; SMN2HTT | |
| SCHEMBL8777441 | 0.81 | CYP1A2 (0.43) | KDM4ECYP1A2LMNASMN1; SMN2HTT | |
| SCHEMBL8777412 | 0.81 | L3MBTL1 (0.46) | CYP1A2L3MBTL1LMNASMN1; SMN2HTT | |
| SCHEMBL8777406 | 0.81 | HAO1 (0.43) | KDM4ECYP1A2L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL29784044 | 0.80 | KDM4E (0.57) | KDM4ECYP1A2L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL45359 | 0.80 | KDM4E (0.57) | KDM4ECYP1A2L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8777404 | 0.80 | KMT2A (0.52) | KDM4ECYP1A2L3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL8777351 | 0.80 | HTT (0.52) | KDM4ECYP1A2L3MBTL1SMN1; SMN2TDP1 | |
| SCHEMBL9607738 | 0.80 | GAA (0.37) | KDM4ECYP1A2LMNAHTTMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069601-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |