Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 7/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.59 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.42 |
| ▸ | METAP1 | P53582 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALPL | P05186 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | ALPI | P09923 | 1/20 | 0.36 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | CCR5 | P51681 | 1/20 | 0.36 |
| ▸ | CCR8 | P51685 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8778633 | 0.86 | GRM5 (0.46) | GRM5KCNH2CYP1A2KDM4ELMNA | |
| SCHEMBL8778606 | 0.81 | CYP1A2 (0.42) | GRM5KCNH2CYP1A2KDM4ELMNA | |
| SCHEMBL45359 | 0.80 | KDM4E (0.57) | CYP1A2METAP1KDM4ETDP1LMNA | |
| SCHEMBL29784044 | 0.80 | KDM4E (0.57) | CYP1A2METAP1KDM4ETDP1LMNA | |
| SCHEMBL8778608 | 0.80 | CYP1A2 (0.40) | GRM5KCNH2CYP1A2 | |
| SCHEMBL8778641 | 0.78 | GRM5 (0.40) | GRM5KCNH2CYP1A2 | |
| SCHEMBL15877252 | 0.75 | GRM5 (1.00) | GRM5KCNH2CYP1A2KDM4ESMN1; SMN2 | |
| SCHEMBL8515946 | 0.74 | KDM4E (0.43) | GRM5CYP1A2METAP1KDM4ETDP1 | |
| SCHEMBL3784385 | 0.72 | RAB9A (0.55) | CYP1A2LMNASMN1; SMN2NPC1RAB9A | |
| SCHEMBL3788203 | 0.72 | CYP1A2 (0.45) | CYP1A2METAP1KDM4ETDP1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012069601-A1 | SUBSTITUTED QUINAZOLINES AS FUNGICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-05-31 | — | — | WO | disclosed |