SCHEMBL453595

SCHEMBL453595

C=C(C(=O)O)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(C)F

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6441428 1.00 THRB (0.33) THRB
SCHEMBL450512 1.00 THRB (0.33) THRB
SCHEMBL709096 1.00 THRB (0.33) THRB
SCHEMBL9546053 0.98 THRB (0.30) THRB
SCHEMBL6062455 0.84
SCHEMBL1491941 0.80 THRB (0.54) THRB
SCHEMBL4395001 0.80 THRB (0.54) THRB
SCHEMBL14879618 0.80 THRB (0.54) THRB
SCHEMBL9546095 0.79 ALDH1A1 (0.33)
Ammonia Solution, Strong SCHEMBL28635848 0.79 THRB (0.52) THRB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023233155-A1 MICRON-SCALE 3D OBJECTS FOR THE MODULATION OF CELL PHENOTYPE FROM PRO TO ANTI-INFLAMMATORY STATES THE UNIVERSITY OF NOTTINGHAM (GB) 2023-12-07 WO claimed
CN-122080723-A Multifunctional electronic moisture-proof coating composition with low dielectric constant 2026-05-26 CN disclosed
WO-2023233155-A1 MICRON-SCALE 3D OBJECTS FOR THE MODULATION OF CELL PHENOTYPE FROM PRO TO ANTI-INFLAMMATORY STATES THE UNIVERSITY OF NOTTINGHAM (GB) 2023-12-07 WO disclosed
EP-4103677-A1 MATERIALS CHEMISTRIES AND MICROTOPOGRAPHIES AND USES THEREOF The University of Nottingham (GB) 2022-12-21 EP disclosed
WO-2021161290-A1 MATERIALS CHEMISTRIES AND MICROTOPOGRAPHIES AND USES THEREOF THE UNIVERSITY OF NOTTINGHAM (GB) 2021-08-19 WO disclosed
EP-3383818-A1 OMNIPHOBIC GROUT ADDITIVE Wacker Chemie AG (DE) 2018-10-10 EP disclosed
US-9809497-B2 Omniphobic grout additive WACKER CHEMICAL CORPORATION (US) 2017-11-07 US disclosed
WO-2017093211-A1 OMNIPHOBIC GROUT ADDITIVE WACKER CHEMIE AG (DE) 2017-06-08 WO disclosed
US-20170152179-A1 OMNIPHOBIC GROUT ADDITIVE WACKER CHEMICAL CORPORATION 2017-06-01 US disclosed
US-9604891-B2 Methods for producing fluorine-containing hydroxyaldehyde, fluorine-containing propanediol, and fluorine-containing alcohol monomer CENTRAL GLASS COMPANY, LIMITED (JP) 2017-03-28 US disclosed
US-20060263886-A1 Fluorous labeling for selective processing of biologically-derived samples PETERS ERIC 2006-11-23 US disclosed
EP-1720067-A1 TOP COAT COMPOSITION Central Glass Company, Limited (JP) 2006-11-08 EP disclosed
US-7122292-B2 Lactone compounds, lactone-containing monomers, their polymers, resist compositions using same, and processes for forming patterns using same CENTRAL GLASS COMPANY, LIMITED (JP) 2006-10-17 US disclosed
US-20060217507-A1 Novel polymerizable acrylate compound containing hexafluorocarbinol group and polymer made therefrom CENTRAL GLASS COMPANY, LIMITED (JP) 2006-09-28 US disclosed
EP-1687643-A1 FLUOROUS LABELING FOR SELECTIVE PROCESSING OF BIOLOGICALLY-DERIVED SAMPLES IRM, LLC (BM) 2006-08-09 EP disclosed
US-20060135744-A1 Fluorinated cyclic compound, polymerizable fluoromonomer, fluoropolymer, resist material comprising the same, and method of forming pattern with the same CENTRAL GLASS COMPANY LIMITED (JP) 2006-06-22 US disclosed
EP-1645554-A1 NOVEL POLYMERIZABLE ACRYLATE COMPOUND CONTAINING HEXAFLUOROCARBINOL GROUP AND POLYMER MADE THEREFROM Central Glass Company, Limited (JP) 2006-04-12 EP disclosed
US-20060057489-A1 Lactone compounds, lactone-containing monomers, their polymers, resist compositions using same, and processes for forming patterns using same CENTRAL GLASS COMPANY, LIMITED (JP) 2006-03-16 US disclosed
US-20050250898-A1 Top coat composition CENTRAL GLASS COMPANY, LIMITED (JP) 2005-11-10 US disclosed
WO-2005050226-A1 FLUOROUS LABELING FOR SELECTIVE PROCESSING OF BIOLOGICALLY-DERIVED SAMPLES IRM LLC (BM) 2005-06-02 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060217507-A1 Novel polymerizable acrylate compound containing hexafluorocarbinol group and polymer made therefrom FGFR1, AFF1, PFAS THRB 3023/4885
US-20060135744-A1 Fluorinated cyclic compound, polymerizable fluoromonomer, fluoropolymer, resist material comprising the same, and method of forming pattern with the same PFAS, AFF1, FUBP1 THRB 4067/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.