SCHEMBL4536056

SCHEMBL4536056

CC(CNc1ccccc1)[SiH](O)O

nearest known ligand 0.49

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.49
SMN1; SMN2 Q16637 3/20 0.43
HTT P42858 1/20 0.43
GAA P10253 3/20 0.40
ALDH1A1 P00352 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
ADRB3 P13945 1/20 0.40
DNM1 Q05193 1/20 0.40
LMNA P02545 1/20 0.38
HPGD P15428 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1674517 0.77 MAPT (0.58) MAPTSMN1; SMN2HTTGAAALDH1A1
SCHEMBL16197831 0.77 MAPT (0.58) MAPTSMN1; SMN2HTTGAAALDH1A1
SCHEMBL182877 0.76 MAPT (0.52) MAPTSMN1; SMN2HTTALDH1A1TDP1
SCHEMBL16192536 0.74 MAPT (0.44) MAPTSMN1; SMN2HTTGAAALDH1A1
Hydrochloric Acid SCHEMBL17710400 0.74 MAPT (0.50) MAPTSMN1; SMN2HTTALDH1A1TDP1
Iodide SCHEMBL29028129 0.74 MAPT (0.50) MAPTSMN1; SMN2HTTALDH1A1TDP1
Ammonia Solution, Strong SCHEMBL6702357 0.74 MAPT (0.50) MAPTSMN1; SMN2HTTALDH1A1TDP1
SCHEMBL7950616 0.73 MAPT (0.50) MAPTSMN1; SMN2HTTGAAALDH1A1
SCHEMBL21843138 0.73 MAPT (0.55) MAPTSMN1; SMN2HTTALDH1A1TDP1
SCHEMBL11048403 0.72 MAPT (0.48) MAPTSMN1; SMN2HTTALDH1A1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7507480-B2 Corrosion-resistant metal surfaces BROOKHAVEN SCIENCE ASSOCIATES, LLC (US) 2009-03-24 US disclosed
US-20060269760-A1 Corrosion-resistant metal surfaces ENERGY, UNITED STATES DEPARTMENT OF 2006-11-30 US disclosed