SCHEMBL1674517

SCHEMBL1674517

CC(O)CNc1ccccc1

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.58
SMN1; SMN2 Q16637 2/20 0.52
HTT P42858 1/20 0.52
DNM1 Q05193 1/20 0.47
ADRB2 P07550 1/20 0.46
ADRB1 P08588 1/20 0.46
ADRB3 P13945 1/20 0.46
ALDH1A1 P00352 2/20 0.46
CYP1A2 P05177 1/20 0.46
CYP2D6 P10635 1/20 0.46
LMNA P02545 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
GAA P10253 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16197831 1.00 MAPT (0.58) MAPTSMN1; SMN2HTTDNM1ADRB2
SCHEMBL28883157 0.83 MAPT (0.55) MAPTSMN1; SMN2HTTADRB2ADRB1
SCHEMBL21843138 0.83 MAPT (0.55) MAPTSMN1; SMN2HTTDNM1ADRB2
SCHEMBL14081111 0.82 IDO1 (0.43) MAPTSMN1; SMN2HTTALDH1A1GAA
SCHEMBL13057591 0.82 ALDH1A1 (0.57) MAPTSMN1; SMN2HTTALDH1A1LMNA
SCHEMBL168120 0.81 MAPT (0.57) MAPTSMN1; SMN2HTTDNM1ADRB2
SCHEMBL182877 0.81 MAPT (0.52) MAPTSMN1; SMN2HTTDNM1ADRB2
SCHEMBL7277860 0.81 MAPT (0.68) MAPTSMN1; SMN2HTTDNM1ADRB2
SCHEMBL22622594 0.80 MAPT (0.54) MAPTSMN1; SMN2HTTALDH1A1GAA
SCHEMBL13057582 0.80 ALDH1A1 (0.46) MAPTSMN1; SMN2ALDH1A1TDP1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2023111389-A1 POLYMER FOAM, METHODS AND USE RELATED THERETO WOODLY OY (FI) 2023-06-22 WO claimed
CN-112409286-B Synthesis method of N-substituted phenyl-5-hydroxymethyl-2-oxazolidinone 杭州迪克科技有限公司 2022-08-05 CN claimed
US-9586913-B2 Processes for the preparation of linezolid using novel intermediates SYMED LABS LIMITED (IN) 2017-03-07 US claimed
CN-103842585-B Press sleeve for a shoe press or conveyor belt based on crosslinked polyurethane formed from mdi-polycarbonate prepolymer 福伊特专利公司 2017-02-15 CN claimed
US-20160102064-A1 IMPROVED PROCESSES FOR THE PREPARATION OF LINEZOLID USING NOVEL INTERMEDIATES SYMED LABS LIMITED (IN) 2016-04-14 US claimed
EP-2989097-A1 IMPROVED PROCESSES FOR THE PREPARATION OF LINEZOLID USING NOVEL INTERMEDIATES Symed Labs Limited (IN) 2016-03-02 EP claimed
WO-2014174522-A1 IMPROVED PROCESSES FOR THE PREPARATION OF LINEZOLID USING NOVEL INTERMEDIATES SYMED LABS LIMITED (IN) 2014-10-30 WO claimed
CN-100460437-C Synthesis method of high-performance multipurpose urethane elastomer CHINA NAT PETROLEUM CORP (CN) 2009-02-11 CN claimed
CN-1919890-A Synthesis method of high-performance multipurpose urethane elastomer CHINA NAT PETROLEUM CORP (CN) 2007-02-28 CN claimed
WO-2024147317-A1 CLEANING COMPOSITION FOR METAL ARTICLES 花王株式会社 2024-07-11 WO disclosed
US-11981929-B2 Use of small molecules to enhance MAFA expression in pancreatic endocrine cells JANSSEN BIOTECH, INC. (US) 2024-05-14 US disclosed
CN-113272352-B Rigid polyurethane foam comprising a silicone-rich nucleating agent 迈图高新材料公司 2024-02-06 CN disclosed
CN-117337310-A Composition based on (meth) acrylate monomers and zinc salts 博斯蒂克股份公司 2024-01-02 CN disclosed
EP-3517553-B1 CATALYST COMPONENT FOR USE IN OLEFIN POLYMERIZATION, CATALYST, AND APPLICATIONS THEREOF CHINA PETROLEUM & CHEM CORP (CN) 2023-11-08 EP disclosed
US-4108791-A POLYETHER AND POLYESTER DIOLS THE DOW CHEMICAL COMPANY (US) 1978-08-22 US disclosed
US-4049716-A Compositions based on polyamines with ether groups RHONE-POULENC INDUSTRIES (FR) 1977-09-20 US disclosed
US-4048102-A CROSSLINKING, MENTHANEDIAMINE, ISOPHORONEDIAMINE THE DOW CHEMICAL COMPANY (US) 1977-09-13 US disclosed
US-4041025-A FOR HYDROPHOBIC FIBERS SUCH AS POLYESTERS, YELLOW TO BLUE-GREEN SHADES BASF AKTIENGESELLSCHAFT (DT) 1977-08-09 US disclosed
US-4007139-A 2,4-DIKETO-1,3,5-HEXAHYDRO-TRIAZINE THE DOW CHEMICAL COMPANY (US) 1977-02-08 US disclosed
US-3933699-A OXAZOLIDINE OR ENAMINE BASF WYANDOTTE CORPORATION (US) 1976-01-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20160102064-A1 IMPROVED PROCESSES FOR THE PREPARATION OF LINEZOLID USING NOVEL INTERMEDIATES CYP3A5, SBDS, MLYCD MAPT 2879/4885SMN1; SMN2 3551/4885HTT 3785/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.