Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201225 | 0.81 | MAPT (0.47) | MAPTSMN1; SMN2NPSR1ALDH1A1TDP1 | |
| SCHEMBL18297303 | 0.77 | MAPT (0.41) | MAPTHTTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL6479794 | 0.75 | TDP1 (0.47) | SMN1; SMN2NPSR1ALDH1A1TDP1GAA | |
| SCHEMBL4536056 | 0.74 | MAPT (0.49) | MAPTHTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL1501527 | 0.73 | SIGMAR1 (0.45) | — | |
| SCHEMBL28658048 | 0.72 | MAPT (0.44) | MAPTSMN1; SMN2NPSR1ALDH1A1TDP1 | |
| SCHEMBL182877 | 0.71 | MAPT (0.52) | MAPTHTTSMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL935506 | 0.71 | MAPT (0.49) | MAPTHTTSMN1; SMN2NPSR1ALDH1A1 | |
| SCHEMBL1854492 | 0.71 | MAPT (0.40) | MAPTHTTNPSR1ALDH1A1GAA | |
| SCHEMBL3340543 | 0.70 | SMN1; SMN2 (0.43) | MAPTHTTSMN1; SMN2ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2796493-A1 | Composition comprising silylated polymers and polyhedral oligomeric metallo silsesquioxane | HUNTSMAN INTERNATIONAL LLC (US) | 2014-10-29 | — | — | EP | disclosed |