Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | HPGDS | O60760 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.36 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.34 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.34 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.34 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.34 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.34 |
| ▸ | GABRD | O14764 | 1/20 | 0.34 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543728 | 0.88 | GAA (0.47) | GAAHPGDSKDM4EGLAGABRA1 | |
| SCHEMBL9753622 | 0.81 | PTGS1 (0.53) | GAAPTGS1PTGS2KDM4EGLA | |
| SCHEMBL4542221 | 0.76 | GAA (0.48) | GAAPTGS1PTGS2KDM4EALDH1A1 | |
| SCHEMBL7975204 | 0.76 | CYP2C9 (0.42) | GAAKDM4ERXFP1MAPTALDH1A1 | |
| SCHEMBL21816403 | 0.73 | TGFBR1 (0.44) | GAAPTGS1PTGS2KDM4EGLA | |
| SCHEMBL7863445 | 0.70 | RAB9A (0.45) | GAAPTGS1PTGS2KDM4EGLA | |
| SCHEMBL8608104 | 0.69 | PTGS1 (0.46) | GAAPTGS1PTGS2KDM4EGLA | |
| SCHEMBL7872399 | 0.68 | MAP2K1 (0.51) | PTGS1PTGS2KDM4ETGFBR1MAPT | |
| SCHEMBL3716081 | 0.68 | PTGS1 (0.49) | GAAPTGS1PTGS2KDM4E | |
| SCHEMBL9941787 | 0.67 | GAA (0.43) | GAAPTGS1PTGS2TGFBR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009140101-A2 | IMIDAZOPYRIDINE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |
| WO-2009140101-A2 | IMIDAZOPYRIDINE COMPOUNDS USEFUL AS MMP-13 INHIBITORS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2009-11-19 | — | — | WO | disclosed |