Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 12/20 | 0.45 |
| ▸ | FPR2 | P25090 | 2/20 | 0.42 |
| ▸ | FPR3 | P25089 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.42 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.42 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 1/20 | 0.41 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536134 | 0.84 | GPR119 (0.42) | GPR119KDM4EMAPTTHRBPTPN2 | |
| SCHEMBL9936121 | 0.84 | GPR119 (0.47) | GPR119FPR2FPR3PTPN2PTPN1 | |
| SCHEMBL4358178 | 0.83 | GPR119 (0.51) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL4536702 | 0.83 | GPR119 (0.49) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL4353381 | 0.82 | GPR119 (0.54) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4353796 | 0.82 | GPR119 (0.55) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4360506 | 0.81 | GPR119 (0.47) | GPR119PTPN2PTPN1PTPN6USP30 | |
| SCHEMBL4353589 | 0.81 | PTPN2 (0.48) | GPR119KDM4EPTPN2PTPN1PTPN6 | |
| SCHEMBL17545463 | 0.81 | GPR119 (0.46) | GPR119FPR2KDM4EMAPTTHRB | |
| SCHEMBL4358492 | 0.80 | GPR119 (0.53) | GPR119PTPN2PTPN1PTPN6USP30 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |