Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 17/20 | 0.54 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.47 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4536702 | 0.92 | GPR119 (0.49) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4353589 | 0.89 | PTPN2 (0.48) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4360506 | 0.89 | GPR119 (0.47) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL13586034 | 0.88 | ABL1 (0.46) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4358178 | 0.88 | GPR119 (0.51) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4355169 | 0.88 | PTPN2 (0.44) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4356930 | 0.88 | HDAC4 (0.50) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4540972 | 0.88 | GPR119 (0.47) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4347832 | 0.87 | GPR119 (0.56) | GPR119PTPN2PTPN1PTPN6 | |
| SCHEMBL4353796 | 0.86 | GPR119 (0.55) | GPR119PTPN2PTPN1PTPN6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |