Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AANAT | Q16613 | 1/20 | 0.80 |
| ▸ | MEN1 | O00255 | 4/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.78 |
| ▸ | MTNR1A | P48039 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 1/20 | 0.71 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.71 |
| ▸ | BLM | P54132 | 1/20 | 0.71 |
| ▸ | GFER | P55789 | 1/20 | 0.66 |
| ▸ | MMP9 | P14780 | 1/20 | 0.64 |
| ▸ | NPC1 | O15118 | 1/20 | 0.64 |
| ▸ | RAB9A | P51151 | 1/20 | 0.64 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.61 |
| ▸ | KDM1A | O60341 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2440677 | 0.91 | MEN1 (0.81) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL7677886 | 0.90 | MEN1 (0.84) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL6424904 | 0.89 | AANAT (0.75) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL6424908 | 0.89 | AANAT (1.00) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL19051489 | 0.88 | MEN1 (0.80) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL761481 | 0.88 | MTNR1A (0.88) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL918966 | 0.86 | MEN1 (0.78) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL918964 | 0.86 | MEN1 (0.78) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL9117842 | 0.85 | MEN1 (0.76) | AANATMEN1KMT2AMTNR1ALMNA | |
| SCHEMBL12762819 | 0.85 | MEN1 (0.76) | AANATMEN1KMT2AMTNR1ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2009-09-24 | — | — | US | disclosed |
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2009-09-24 | — | — | US | disclosed |
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | UNIVERSITA DEGLI STUDI DI SIENA (IT) | 2009-09-24 | — | — | US | disclosed |
| CN-101137645-A | Arylpiperazine derivatives for the treatment of neuropsychiatric disorders | UNIV SIENA (IT) | 2008-03-05 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090238761-A1 | Novel Aryl Piperazine Derivatives With Medical Utility | HTR2C, HTR2A, DRD2 | AANAT 42/4885MEN1 4547/4885KMT2A 1667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.