Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.52 |
| ▸ | RAB9A | P51151 | 2/20 | 0.52 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.52 |
| ▸ | LCK | P06239 | 3/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | RECQL | P46063 | 1/20 | 0.46 |
| ▸ | BLM | P54132 | 3/20 | 0.45 |
| ▸ | GFER | P55789 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | ALPG | P10696 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5065668 | 0.79 | ADRB2 (0.47) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| SCHEMBL11805095 | 0.79 | KDM4E (0.60) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| SCHEMBL11520449 | 0.74 | LCK (0.47) | KDM4ERAB9ALCKALDH1A1CYP3A4 | |
| SCHEMBL21049763 | 0.74 | ALDH1A1 (0.63) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| SCHEMBL28165888 | 0.72 | KDM4E (0.58) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| SCHEMBL21412902 | 0.72 | LCK (0.45) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| Protocatechualdehyde SCHEMBL29196221 | 0.70 | KDM4E (0.91) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| Protocatechualdehyde SCHEMBL28985147 | 0.70 | KDM4E (0.58) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| Protocatechualdehyde SCHEMBL27648161 | 0.69 | KDM4E (0.79) | KDM4ERAB9APTGS2LCKALDH1A1 | |
| SCHEMBL17308143 | 0.69 | EGFR (0.69) | KDM4ERAB9ALCKALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2637649-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | Akron Molecules GmbH (AT) | 2013-09-18 | — | — | EP | disclosed |
| WO-2012062925-A2 | COMPOUNDS AND METHODS FOR TREATING PAIN | AKRON MOLECULES GMBH (AT) | 2012-05-18 | — | — | WO | disclosed |