Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNK3 | O14649 | 1/20 | 0.50 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.46 |
| ▸ | TAOK3 | Q9H2K8 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | LNPEP | Q9UIQ6 | 3/20 | 0.45 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.45 |
| ▸ | PPARG | P37231 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | PTGER4 | P35408 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.42 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.42 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537762 | 0.92 | PPARG (0.48) | LNPEPPPARGMAPTHDAC1HDAC8 | |
| SCHEMBL8034344 | 0.89 | PPARG (0.54) | PPARGMAPTHDAC1 | |
| SCHEMBL8032490 | 0.87 | PPARG (0.55) | PPARGHDAC1 | |
| SCHEMBL8034539 | 0.85 | PPARG (0.56) | PPARGTAS1R3TAS1R1HDAC1HDAC8 | |
| SCHEMBL4540765 | 0.85 | MEN1 (0.52) | PPARGMAPTHDAC1HDAC8HDAC6 | |
| SCHEMBL4536613 | 0.85 | MAPT (0.55) | KCNK3MAPTRAB9APTGER4 | |
| SCHEMBL8028550 | 0.83 | PPARG (0.58) | PPARGMAPTTAS1R3TAS1R1 | |
| SCHEMBL8040416 | 0.83 | PPARG (0.58) | PPARGTAS1R3TAS1R1 | |
| SCHEMBL8038740 | 0.82 | PPARG (0.57) | PPARG | |
| SCHEMBL8034326 | 0.82 | PPARG (0.48) | PPARGTAS1R3TAS1R1HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |
| WO-2009083526-A1 | NOVEL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2009-07-09 | — | — | WO | disclosed |