SCHEMBL453733

SCHEMBL453733

NC(=S)c1ccccn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5411092 1.00 CES2 (0.54)
SCHEMBL30438706 1.00
Hydrochloric Acid SCHEMBL397305 0.98 CES2 (0.52)
Trifluoroacetic Acid SCHEMBL31078804 0.84 LMNA (0.52)
SCHEMBL15818192 0.80 CES2 (0.58)
SCHEMBL15818190 0.80 CES2 (0.58)
SCHEMBL11088701 0.80 CES2 (0.58)
SCHEMBL4341948 0.79 ALDH1A1 (0.48)
SCHEMBL5997996 0.78 KDM4E (0.59)
SCHEMBL23072551 0.78

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 441 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118676384-A S, N co-doped iron-carbon catalyst and preparation method and application thereof 中国科学院大连化学物理研究所 2024-09-20 CN claimed
EP-4423083-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES Istanbul Medipol Universitesi (TR) 2024-09-04 EP claimed
WO-2023096623-A2 SYNTHESIS OF PYRAZOLONE DERIVATIVE COMPOUNDS AND THEIR EFFECTS ON COX ENZYMES İSTANBUL MEDİPOL ÜNİVERSİTESİ (TR) 2023-06-01 WO claimed
CN-114990587-A Electrochemical synthesis method of thiazole compound 华南理工大学 2022-09-02 CN claimed
EP-1014200-B1 Method of developing photosensitive lithographic printing plate precursor FUJIFILM CORP (JP) 2015-03-18 EP claimed
CN-103958473-A Amide compound, composition and application thereof ADVINUS THERAPEUTICS LTD 2014-07-30 CN claimed
US-20030190555-A1 Image forming method FUJI PHOTO FILM CO., LTD. 2003-10-09 US claimed
EP-1346843-A1 Image forming method Fuji Photo Film Co., Ltd. (JP) 2003-09-24 EP claimed
CN-1332743-A Cell adhesion-inhibiting antinflammatory compounds ABBOTT CO (US) 2002-01-23 CN claimed
US-4101507-A WITH PICOLINAMIDES AND ZINC OXIDE OR MAGNESIUM OXIDE THE FIRESTONE TIRE & RUBBER COMPANY (US) 1978-07-18 US claimed
US-6423458-B1 None US disclosed
EP-4743081-A1 MODULATORS OF MITOCHONDRIAL DNA REPLICATION Pretzel Therapeutics, Inc. (US) 2026-05-20 EP disclosed
US-20260008788-A1 AZA-FUSED RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE SUZHOU ARK BIOPHARMACEUTICAL CO LTD (CN) 2026-01-08 US disclosed
US-20250351828-A1 AZOLE FUNGICIDE COMPOSITION ADAMA MAKHTESHIM LTD. (IL) 2025-11-20 US disclosed
EP-4596554-A1 AZA-FUSED RING COMPOUND, PREPARATION METHOD THEREFOR, AND USE THEREOF IN MEDICINE Suzhou Arkbiopharmaceutical Co., Ltd. (CN) 2025-08-06 EP disclosed
US-4873238-A ANTIULCER AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1989-10-10 US disclosed
US-4873238-A ANTIULCER AGENTS AMERICAN HOME PRODUCTS CORPORATION (US) 1989-10-10 US disclosed
US-4203897-A Penam derivatives FUJISAWA PHARMACEUTICAL COMPANY, LIMITED (JP) 1980-05-20 US disclosed
US-4084049-A CEPHALOSPORIN ANTIBIOTICS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1978-04-11 US disclosed
US-3954732-A BACTERICIDAL PENICILLINS FUJISAWA PHARMACEUTICAL CO., LTD. (JA) 1976-05-04 US disclosed