Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.47 |
| ▸ | CASP7 | P55210 | 1/20 | 0.47 |
| ▸ | CASP9 | P55211 | 1/20 | 0.47 |
| ▸ | F9 | P00740 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4379511 | 0.86 | KDM4E (0.45) | KDM4ECASP3CASP7CASP9F9 | |
| SCHEMBL4786081 | 0.82 | MAPT (0.64) | MAPTHPGDRAB9ANPC1LMNA | |
| SCHEMBL4373468 | 0.81 | MAPT (0.59) | KDM4EMAPTHPGDRAB9ALMNA | |
| SCHEMBL707685 | 0.79 | GAA (0.64) | KDM4EMAPTHPGDLMNAPOLB | |
| SCHEMBL4373011 | 0.76 | HPGD (0.49) | KDM4EMAPTHPGDRAB9ALMNA | |
| SCHEMBL31520212 | 0.76 | TSHR (0.67) | KDM4ECASP3CASP7CASP9F9 | |
| SCHEMBL9619575 | 0.76 | ESR1 (0.57) | MAPTUSP2HPGDRAB9APOLB | |
| SCHEMBL4543869 | 0.76 | ESR1 (0.57) | MAPTUSP2HPGDRAB9APOLB | |
| SCHEMBL11490448 | 0.76 | TSHR (0.67) | KDM4ECASP3CASP7CASP9F9 | |
| SCHEMBL4787301 | 0.74 | F2 (0.47) | KDM4EMAPTHPGDRAB9ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009118747-A1 | NOVEL HYDROXY FUNCTIONALIZED 1, 2, 4-TRIOXANES AS ANTIMALARIAL AGENTS AND A PROCESS FOR THE PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2009-10-01 | — | — | WO | disclosed |