Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 12/20 | 0.57 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.57 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | MEN1 | O00255 | 5/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | GAA | P10253 | 4/20 | 0.49 |
| ▸ | JAK2 | O60674 | 1/20 | 0.49 |
| ▸ | USP2 | O75604 | 1/20 | 0.49 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ESRRA | P11474 | 2/20 | 0.46 |
| ▸ | STS | P08842 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4543869 | 1.00 | ESR1 (0.57) | ESR1ESR2MAPTHPGDRAB9A | |
| SCHEMBL4786081 | 0.92 | MAPT (0.64) | ESR1ESR2MAPTHPGDRAB9A | |
| SCHEMBL10588626 | 0.83 | MAPT (0.62) | MAPTHPGDRAB9AKMT2AGAA | |
| SCHEMBL10825749 | 0.83 | HPGD (0.56) | MAPTHPGDRAB9AMEN1KMT2A | |
| SCHEMBL10331769 | 0.80 | ESR1 (0.48) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL4743462 | 0.80 | MAPT (0.49) | ESR1ESR2MAPTHPGDRAB9A | |
| SCHEMBL7531116 | 0.78 | ESR1 (0.54) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL10825738 | 0.77 | ESRRA (0.68) | MAPTHPGDRAB9AMEN1KMT2A | |
| SCHEMBL10331748 | 0.76 | ESR1 (0.44) | ESR1ESR2MAPTMEN1KMT2A | |
| SCHEMBL4537812 | 0.76 | KDM4E (0.50) | MAPTHPGDRAB9AGAAUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0467826-A2 | Linear polymers | CIBA-GEIGY AG (CH) | 1992-01-22 | — | — | EP | disclosed |