SCHEMBL4538237

SCHEMBL4538237

O=P(O)(O)CCC[Si](O)(O)O

nearest known ligand 0.58

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.58
LMNA P02545 1/20 0.48
CYP3A4 P08684 1/20 0.48
NFKB1 P19838 1/20 0.48
BLM P54132 1/20 0.48
PMP22 Q01453 1/20 0.48
LPAR3 Q9UBY5 3/20 0.44
LPAR2 Q9HBW0 1/20 0.44
BBOX1 O75936 2/20 0.42
ALDH1A1 P00352 3/20 0.39
TDP1 Q9NUW8 1/20 0.39
ENPEP Q07075 1/20 0.37
ANPEP P15144 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18391 0.92 TYMS (0.55) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL5486639 0.82 TYMS (0.47) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL26037359 0.79 S1PR2 (0.47) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL20235 0.75 TYMS (0.85) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL182326 0.75 TYMS (1.00) TYMSLMNACYP3A4NFKB1BLM
Ammonia Solution, Strong SCHEMBL1777238 0.72 TYMS (0.92) TYMSLMNACYP3A4NFKB1BLM
Ammonia Solution, Strong SCHEMBL1643223 0.72 TYMS (0.92) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL767546 0.72 TYMS (0.79) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL1636300 0.72 TYMS (0.79) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL3211535 0.72 TYMS (0.79) TYMSLMNACYP3A4NFKB1BLM

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7575832-B2 Porous dielectric coating; electrolytes; trihydroxysilylpropylphosphonic acid as conductive material DEGUSSA AG (DE) 2009-08-18 US claimed
US-7575832-B2 Porous dielectric coating; electrolytes; trihydroxysilylpropylphosphonic acid as conductive material DEGUSSA AG (DE) 2009-08-18 US disclosed
US-20060166085-A1 Porous dielectric coating; electrolytes; trihydroxysilylpropylphosphonic acid as conductive material CREAVIS GESELLSCHAFT FUER TECH. UND INNOVATION MBH (DE) 2006-07-27 US disclosed
EP-1532701-B1 ION CONDUCTING BATTERY SEPARATOR FOR LITHIUM BATTERIES, METHOD FOR THE PRODUCTION AND USE THEREOF DEGUSSA (DE) 2006-01-04 EP disclosed
EP-1532701-A1 ION CONDUCTING BATTERY SEPARATOR FOR LITHIUM BATTERIES, METHOD FOR THE PRODUCTION AND USE THEREOF Degussa AG (DE) 2005-05-25 EP disclosed
WO-2004021477-A1 ION CONDUCTING BATTERY SEPARATOR FOR LITHIUM BATTERIES, METHOD FOR THE PRODUCTION AND USE THEREOF CREAVIS GESELLSCHAFT FÜR TECHNOLOGIE UND INNOVATION MBH (DE) 2004-03-11 WO disclosed