Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR2 | O95136 | 9/20 | 0.47 |
| ▸ | S1PR1 | P21453 | 9/20 | 0.47 |
| ▸ | S1PR3 | Q99500 | 9/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 8/20 | 0.47 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.47 |
| ▸ | PGK1 | P00558 | 1/20 | 0.41 |
| ▸ | PGK2 | P07205 | 1/20 | 0.41 |
| ▸ | TYMS | P04818 | 1/20 | 0.40 |
| ▸ | BLM | P54132 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | ANPEP | P15144 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | HPRT1 | P00492 | 1/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26841121 | 0.83 | S1PR2 (0.48) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL4538237 | 0.79 | TYMS (0.58) | TYMSBLMLMNACYP3A4NFKB1 | |
| SCHEMBL4966489 | 0.78 | TYMS (0.53) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL18391 | 0.77 | TYMS (0.55) | TYMSBLMLMNACYP3A4NFKB1 | |
| SCHEMBL2596965 | 0.76 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2596887 | 0.74 | S1PR2 (0.47) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL5486639 | 0.73 | TYMS (0.47) | PGK1PGK2TYMSBLMLMNA | |
| SCHEMBL371420 | 0.73 | BLM (0.61) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL5595548 | 0.73 | S1PR2 (0.73) | S1PR2S1PR1S1PR3S1PR4S1PR5 | |
| SCHEMBL2596914 | 0.72 | S1PR2 (0.46) | S1PR2S1PR1S1PR3S1PR4S1PR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11827807-B2 | Metal surface coatings for improving bond performance and methods of making the same | NOVELIS INC. (US) | 2023-11-28 | — | — | US | disclosed |
| EP-3997180-B1 | METAL SURFACE COATINGS FOR IMPROVING BOND PERFORMANCE AND METHODS OF MAKING THE SAME | NOVELIS INC (US) | 2023-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11827807-B2 | Metal surface coatings for improving bond performance and methods of making the same | SOD1, AEBP2, ITGA8 | S1PR2 4654/4885S1PR1 4703/4885S1PR3 4753/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.