SCHEMBL18391

SCHEMBL18391

O=P(O)(O)CCCC[Si](O)(O)O

nearest known ligand 0.55

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
TYMS P04818 1/20 0.55
LPAR3 Q9UBY5 3/20 0.48
LPAR2 Q9HBW0 1/20 0.48
LMNA P02545 1/20 0.46
CYP3A4 P08684 1/20 0.46
NFKB1 P19838 1/20 0.46
BLM P54132 1/20 0.46
PMP22 Q01453 1/20 0.46
BBOX1 O75936 2/20 0.41
ALDH1A1 P00352 3/20 0.38
TDP1 Q9NUW8 1/20 0.38
ENPEP Q07075 1/20 0.35
ANPEP P15144 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4538237 0.92 TYMS (0.58) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL5486639 0.80 TYMS (0.47) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL20235 0.80 TYMS (0.85) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL26037359 0.77 S1PR2 (0.47) TYMSLMNACYP3A4NFKB1BLM
SCHEMBL3211535 0.76 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL767546 0.76 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL1636300 0.76 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL7902534 0.76 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
SCHEMBL9701682 0.76 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4
Ammonia Solution, Strong SCHEMBL2319488 0.76 TYMS (0.79) TYMSLPAR3LPAR2LMNACYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 262 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250277134-A1 SILANE MODIFICATION OF CERIA NANOPARTICLES IN COLLOIDALLY STABLE SOLUTIONS CMC MATERIALS LLC 2025-09-04 US claimed
US-12371550-B2 Method for fabricating nano-particle having perovskite crystalline structure and resin composition including the nano-particle KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2025-07-29 US claimed
CN-113874318-B Method for obtaining mesoporous silica particle-supported metal oxides 柏林工业大学 2024-05-07 CN claimed
US-20230073504-A1 METHOD FOR FABRICATING NANO-PARTICLE HAVING PEROVSKITE CRYSTALLINE STRUCTURE AND RESIN COMPOSITION INCLUDING THE NANO-PARTICLE KOREA INSTITUTE OF MACHINERY & MATERIALS (KR) 2023-03-09 US claimed
CN-115254009-A Preparation method of blood perfusion device filler for reducing uric acid concentration 江苏恰瑞生物科技有限公司 2022-11-01 CN claimed
CN-113874318-A Method for obtaining mesoporous silica particle-supported metal oxide 柏林工业大学 2021-12-31 CN claimed
CN-107753464-B Hollow silica nanoparticles encapsulating bioactive components, methods of making and uses thereof 牟中原 2021-11-16 CN claimed
CN-113499319-A Hollow silica nanoparticles encapsulating bioactive components, methods of making and uses thereof 牟中原 2021-10-15 CN claimed
CN-111870699-A Surface-modified mesoporous silica nanoparticles, method for producing same, and use thereof 奈力生医股份有限公司 2020-11-03 CN claimed
EP-2669269-B1 NITRIC OXIDE-RELEASING PARTICLES FOR NITRIC OXIDE THERAPEUTICS AND BIOMEDICAL APPLICATIONS UNIV NORTH CAROLINA CHAPEL HILL (US) 2019-05-22 EP claimed
US-20100147515-A1 SURFACE MODIFICATION FOR CROSS-LINKING OR BREAKING INTERACTIONS WITH INJECTED FLUID SCHLUMBERGER TECHNOLOGY CORPORATION 2010-06-17 US claimed
WO-2009069959-A2 A NANOPARTICLE FOR SEPARATING PEPTIDE, METHOD FOR PREPARING THE SAME, AND METHOD FOR SEPARATING PEPTIDE USING THE SAME KOREA UNIVERSITY INDUSTRIAL & ACADEMIC COLLABORATION FOUNDATION (KR) 2009-06-04 WO claimed
US-20090087381-A1 CHELATOR-FUNCTIONALIZED NANOPARTICLES GENERAL ELECTRIC COMPANY (US) 2009-04-02 US claimed
US-6733828-B2 Method of fabricating nanostructured materials NATIONAL TSING HUA UNIVERSITY (TW) 2004-05-11 US claimed
US-20040028913-A1 Cation-conducting or proton-conducting ceramic membrane based on a hydroxysilylic acid, method for the production thereof and use of the same HENNIGE VOLKER (DE) 2004-02-12 US claimed
US-20030191205-A1 MOLECULARLY-IMPRINTED MATERIAL MADE BY TEMPLATE-DIRECTED SYNTHESIS MARKOWITZ MICHAEL A (US) 2003-10-09 US claimed
US-20030139483-A1 Molecularly-imprinted material made by template-directed synthesis NAVY, SECRETARY OF THE, THE UNITED STATES OF AMERICA AS, REPRESENTED BY THE 2003-07-24 US claimed
US-20020065334-A1 Molecularly-imprinted material made by template-directed synthesis UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE NAVY, THE 2002-05-30 US claimed
US-6221944-B1 SURFACE TREATMENT EMORY UNIVERSITY 2001-04-24 US claimed
EP-0669385-B1 USE OF SILICONE RELEASE AGENT DOW CORNING (US) 1999-07-07 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090087381-A1 CHELATOR-FUNCTIONALIZED NANOPARTICLES SLC40A1, TFRC, SLC19A1 TYMS 1582/4885LPAR3 4062/4885LPAR2 4344/4885
US-20030139483-A1 Molecularly-imprinted material made by template-directed synthesis POLM, SGMS1, MSI2 TYMS 2966/4885LPAR3 557/4885LPAR2 694/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.