6-Chloronicotinaldehyde

6-Chloronicotinaldehyde

SCHEMBL453853

O=Cc1ccc(Cl)nc1

nearest known ligand 0.00

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⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
6-Chloronicotinaldehyde SCHEMBL29694763 1.00
6-Chloronicotinaldehyde SCHEMBL27615551 0.98 ALDH1A1 (0.49)
SCHEMBL4598044 0.81 ALDH1A1 (0.63)
SCHEMBL12640351 0.79 MAPT (0.53)
SCHEMBL30547492 0.79 NFE2L2 (0.49)
SCHEMBL12694562 0.79 NFE2L2 (0.49)
SCHEMBL16838776 0.78 ALDH1A1 (0.51)
SCHEMBL12577895 0.77 ALDH1A1 (0.61)
SCHEMBL7015014 0.77 NAPRT (0.55)
SCHEMBL3368746 0.76

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1810 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3356387-B1 ANTIMICROBIAL POLYMYXIN DERIVATIVE COMPOUNDS UNIV MONASH (AU) 2024-06-26 EP claimed
CN-117867188-A Bio-based ligand for chromium-free metal tanning agent 温州大学 2024-04-12 CN claimed
CN-116640106-B Phenylpiperazine compound and preparation method and application thereof 郑州大学 2024-03-08 CN claimed
CN-116640106-A Phenylpiperazine compound and preparation method and application thereof 郑州大学 2023-08-25 CN claimed
CN-115819404-B Rapid detection device and detection method for pymetrozine in agricultural products 佛山职业技术学院 2023-04-18 CN claimed
CN-115819404-A Rapid detection device and detection method for pymetrozine in agricultural products 佛山职业技术学院 2023-03-21 CN claimed
US-11225505-B2 Antimicrobial polymyxin derivative compounds MONASH UNIVERSITY (AU) 2022-01-18 US claimed
CN-113277975-A Deuterated flurobenzapine and preparation method and application thereof 深圳鼎邦生物科技有限公司 2021-08-20 CN claimed
CN-109761959-B Method for synthesizing Abemaciclib mesylate 杭州科巢生物科技有限公司 2020-09-08 CN claimed
CN-109761959-A A kind of novel synthesis of Abemaciclib mesylate 杭州科巢生物科技有限公司 2019-05-17 CN claimed
WO-2001000594-A1 TRIAZOLE COMPOUNDS AND COMBINATORIAL LIBRARIES THEREOF LION BIOSCIENCE AG (DE) 2001-01-04 WO claimed
EP-0977989-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 2000-02-09 EP claimed
WO-1998034115-A1 4-SUBSTITUTED-QUINOLINE DERIVATIVES AND 4-SUBSTITUTE-QUINOLINE COMBINATORIAL LIBRARIES TREGA BIOSCIENCES, INC. (US) 1998-08-06 WO claimed
EP-0542086-B1 Process for the preparation of the N-[(2-chloropyridin-5-yl)methyl]-ethylenediamine BAYER AG (DE) 1994-11-02 EP claimed
US-5352794-A Process for the preparation of N-(2-chloro-pyridin-5-yl-methyl)ethylenediamine BAYER AKTIENGESELLSCHAFT (DE) 1994-10-04 US claimed
EP-0383091-B1 Insecticidally active nitro compounds BAYER AGROCHEM KK (JP) 1993-11-10 EP claimed
EP-0542086-A1 Process for the preparation of the N-[(2-chloropyridin-5-yl)methyl]-ethylenediamine BAYER AG (DE) 1993-05-19 EP claimed
US-5204359-A Insecticidally active nitro compounds NIHON BAYER AGROCHEM K.K. (JP) 1993-04-20 US claimed
US-5084467-A INSECTICIDALLY ACTIVE NITRO GUANIDINE COMPOUNDS NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1992-01-28 US claimed
EP-0383091-A1 Insecticidally active nitro compounds NIHON BAYER AGROCHEM K.K. (JP) 1990-08-22 EP claimed